Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD1 | P21728 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19354447 | 1.00 | CHRM2 (0.53) | CHRM2CHRM1CHRM3ENPP2OPRM1 | |
| SCHEMBL27479318 | 0.98 | CHRM2 (0.52) | CHRM2CHRM1CHRM3ENPP2OPRM1 | |
| SCHEMBL2965194 | 0.87 | PNMT (0.47) | CHRM1OPRK1HTR2AADRA1AHTR2B | |
| SCHEMBL4531632 | 0.85 | ALOX15 (0.55) | CHRM2CHRM1CHRM3ENPP2OPRM1 | |
| SCHEMBL647401 | 0.85 | OPRM1 (0.54) | CHRM2CHRM1CHRM3ENPP2OPRM1 | |
| SCHEMBL19342844 | 0.84 | ADRB1 (0.50) | CHRM2CHRM1CHRM3ENPP2OPRM1 | |
| Gepefrine SCHEMBL2562808 | 0.83 | TAAR1 (0.61) | ENPP2ADRB1MIFHTR2AADRA1A | |
| Gepefrine SCHEMBL149774 | 0.83 | TAAR1 (0.61) | ENPP2ADRB1MIFHTR2AADRA1A | |
| Gepefrine SCHEMBL30011768 | 0.83 | TAAR1 (0.61) | ENPP2ADRB1MIFHTR2AADRA1A | |
| Gepefrine SCHEMBL265538 | 0.83 | TAAR1 (0.61) | ENPP2ADRB1MIFHTR2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113786287-B | Paper diaper and preparation method thereof | 福建恒安集团有限公司 | 2022-07-05 | — | — | CN | claimed |
| CN-113786287-A | Paper diaper and preparation method thereof | 福建恒安集团有限公司 | 2021-12-14 | — | — | CN | claimed |
| EP-1023263-B1 | NOVEL VITAMIN D ANALOGUES | LEO PHARM PROD LTD (DK) | 2002-06-12 | — | — | EP | claimed |
| EP-0327361-B1 | 3-(2-HYDROPEROXY-2-PROPYL)PHENOL AND METHOD OF PRODUCING RESORCINOL USING THE SAME | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-17 | — | — | EP | claimed |
| EP-0327361-A1 | 3-(2-hydroperoxy-2-propyl)phenol and method of producing resorcinol using the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-08-09 | — | — | EP | claimed |
| US-4755188-A | Aqueous composition for oxidative hair coloring containing developer-coupler combination with substituted phenol coupler | WELLA AKTIENGESELLSCHAFT (DE) | 1988-07-05 | — | — | US | claimed |
| JP-1199926-A | — | — | None | — | — | JP | disclosed |
| CN-113786287-B | Paper diaper and preparation method thereof | 福建恒安集团有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-113786287-A | Paper diaper and preparation method thereof | 福建恒安集团有限公司 | 2021-12-14 | — | — | CN | disclosed |
| US-20180327354-A1 | Unnatural Analogues of Calcitriol and Uses Thereof | VIDASYM, LLC | 2018-11-15 | — | — | US | disclosed |
| EP-2419403-B1 | VITAMIN D RECEPTOR AGONISTS AND USES THEREOF | VIDASYM INC (US) | 2016-09-07 | — | — | EP | disclosed |
| US-20120115824-A1 | Vitamin D Receptor Agonists and Uses Thereof | VIDASYM, LLC (US) | 2012-05-10 | — | — | US | disclosed |
| EP-2419403-A1 | VITAMIN D RECEPTOR AGONISTS AND USES THEREOF | Vidasym, Llc (US) | 2012-02-22 | — | — | EP | disclosed |
| US-5030767-A | Decomposition, solvent, inorganic acid or arenesulfonic acid as catalyst | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-07-09 | — | — | US | disclosed |
| US-5030767-A | Decomposition, solvent, inorganic acid or arenesulfonic acid as catalyst | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-07-09 | — | — | US | disclosed |
| US-4920132-A | Quinoline derivatives and use thereof as antagonists of leukotriene D4 | RORER PHARMACEUTICAL CORP. (US) | 1990-04-24 | — | — | US | disclosed |
| JP-H01199926-A | 3-(2-HYDROPEROXY-2-PROPYL)PHENOL AND PREPARATION OF RESORCINOL FROM SAID COMPOUND | MITSUI PETROCHEM IND LTD | 1989-08-11 | — | — | JP | disclosed |
| EP-0327361-A1 | 3-(2-hydroperoxy-2-propyl)phenol and method of producing resorcinol using the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-08-09 | — | — | EP | disclosed |
| EP-0327361-A1 | 3-(2-hydroperoxy-2-propyl)phenol and method of producing resorcinol using the same | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1989-08-09 | — | — | EP | disclosed |
| WO-1989004305-A1 | QUINOLINE DERIVATIVES AS ANTAGONISTS OF LEUKOTRIENE D4 | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-05-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115824-A1 | Vitamin D Receptor Agonists and Uses Thereof | VDR, CYP2R1, CYP24A1 | CHRM2 957/4885CHRM1 1081/4885CHRM3 1445/4885 |
| US-20180327354-A1 | Unnatural Analogues of Calcitriol and Uses Thereof | VDR, CYP2R1, CYP24A1 | CHRM2 1705/4885CHRM1 1912/4885CHRM3 2939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.