SCHEMBL6299667

SCHEMBL6299667

COC(=O)CC[C@@H](NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.56
SIRT2 Q8IXJ6 1/20 0.55
SIRT1 Q96EB6 1/20 0.55
ALDH1A1 P00352 1/20 0.54
ALOX15 P16050 1/20 0.54
PPARA Q07869 3/20 0.54
PPARG P37231 1/20 0.54
CTSK P43235 3/20 0.53
KYNU Q16719 1/20 0.53
CTSL P07711 1/20 0.52
CTSB P07858 1/20 0.52
CTSS P25774 1/20 0.52
CASP1 P29466 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL220498 1.00 FOLH1 (0.56) FOLH1SIRT2SIRT1ALDH1A1ALOX15
SCHEMBL5970693 1.00 FOLH1 (0.56) FOLH1SIRT2SIRT1ALDH1A1ALOX15
SCHEMBL7087075 0.92 KYNU (0.59) SIRT2SIRT1ALDH1A1ALOX15CTSK
SCHEMBL11053442 0.92 KYNU (0.59) SIRT2SIRT1ALDH1A1ALOX15CTSK
SCHEMBL6849362 0.92 FOLH1 (0.58) FOLH1SIRT2SIRT1PPARAPPARG
SCHEMBL11893028 0.92 FOLH1 (0.58) FOLH1SIRT2SIRT1PPARAPPARG
SCHEMBL7373019 0.92 FOLH1 (0.58) FOLH1SIRT2SIRT1PPARAPPARG
SCHEMBL9351629 0.91 FOLH1 (0.53) FOLH1SIRT2SIRT1ALDH1A1ALOX15
SCHEMBL16789581 0.91 SIRT2 (0.64) FOLH1SIRT2SIRT1ALDH1A1ALOX15
SCHEMBL20696435 0.91 ALDH1A1 (0.59) ALDH1A1ALOX15CTSKKYNUCTSL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114980933-B Compositions and methods for treating viral infections 奇达拉治疗公司 2025-01-07 CN disclosed
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS CIDARA THERAPEUTICS, INC. 2023-12-14 US disclosed
US-11833213-B2 Compositions and methods for the treatment of viral infections CIDARA THERAPEUTICS, INC. (US) 2023-12-05 US disclosed
US-6924307-B2 Aminobutyric acid derivatives and pharmaceutical composition containing the same as active ingredient ONO PHARMACEUTICAL CO., LTD. (JP) 2005-08-02 US disclosed
US-20040002480-A1 Aminobutyric acid derivatives and pharmaceutical composition containing the same as active ingredient TAKAHASHI KANJI (JP) 2004-01-01 US disclosed
US-6569899-B1 Such as 5-ethoxymethoxy-4(S)-(N-(4-iodophenylcarbonyl)amino) pentanoic acid methyl ester for inhibiting matrix metalloproteinase; for treatment of rheumatoid diseases, arthrosteitis, osteoarthritis, and osteoporosis ONO PHARMACEUTICALS CO., LTD. (JP) 2003-05-27 US disclosed
EP-1167346-A1 4-AMINOBUTANOIC ACID DERIVATIVES AND DRUGS CONTAINING THESE DERIVATIVES AS THE ACTIVE INGREDIENT ONO PHARMACEUTICAL CO., LTD. (JP) 2002-01-02 EP disclosed
EP-0209237-A2 Vinyl-glycyl-amino-beta-lactam derivatives BEECHAM GROUP PLC (GB) 1987-01-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398226-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS FCGR3B, ALB, FCGR1A FOLH1 1206/4885SIRT2 2929/4885SIRT1 2103/4885
US-11833213-B2 Compositions and methods for the treatment of viral infections FCGR3B, ALB, FCGR1A FOLH1 1206/4885SIRT2 2929/4885SIRT1 2103/4885
US-20040002480-A1 Aminobutyric acid derivatives and pharmaceutical composition containing the same as active ingredient GABBR1, GABRB1, GABBR2 FOLH1 677/4885SIRT2 3175/4885SIRT1 2011/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.