Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300285 | 0.86 | NPC1 (0.41) | MAOBHRH3KCNH2HRH1NPC1 | |
| SCHEMBL4672123 | 0.77 | MAPKAPK2 (0.46) | PARP10TSHR | |
| SCHEMBL4675102 | 0.76 | ALDH1A1 (0.42) | PARP10TSHRMEN1KMT2ANPC1 | |
| SCHEMBL4670479 | 0.75 | ALDH1A1 (0.39) | PARP10TSHRMEN1KMT2A | |
| SCHEMBL4673352 | 0.74 | MAPK1 (0.50) | TSHRMEN1KMT2A | |
| SCHEMBL4670081 | 0.74 | ADRB2 (0.42) | PARP10MAOBTSHRHRH3NPC1 | |
| SCHEMBL6301319 | 0.74 | PARP10 (0.41) | PARP10MAOBTSHRHRH3MEN1 | |
| Water SCHEMBL4673066 | 0.73 | ADRB2 (0.41) | PARP10MAOBTSHRHRH3 | |
| SCHEMBL4670046 | 0.73 | PARP10 (0.40) | PARP10MAOBTSHRHRH3MEN1 | |
| Water SCHEMBL4672106 | 0.73 | ADRB2 (0.41) | PARP10MAOBTSHRHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6903218-B2 | Sulfonamide substituted chroman derivatives | BAYER PHARMACEUTICALS CORPORATION (US) | 2005-06-07 | — | — | US | disclosed |