Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.46 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4672126 | 0.86 | NPBWR1 (0.42) | DRD2SMN1; SMN2LMNAMAPTNPBWR1 | |
| SCHEMBL4673352 | 0.85 | MAPK1 (0.50) | PARP1PARP2ALDH1A1HPGDTSHR | |
| SCHEMBL4672086 | 0.80 | KCNJ1 (0.53) | ALDH1A1SMN1; SMN2LMNAMAPTHPGD | |
| SCHEMBL4675102 | 0.77 | ALDH1A1 (0.42) | PARP10ALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL4670479 | 0.77 | ALDH1A1 (0.39) | MAPKAPK2PARP10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL6300283 | 0.77 | PARP10 (0.47) | PARP10TSHR | |
| SCHEMBL4670081 | 0.73 | ADRB2 (0.42) | PARP10PARP2ALDH1A1TSHR | |
| Water SCHEMBL4673066 | 0.72 | ADRB2 (0.41) | PARP10PARP2ALDH1A1TSHR | |
| SCHEMBL4670046 | 0.72 | PARP10 (0.40) | PARP10PARP2ALDH1A1TSHRKDM4E | |
| SCHEMBL4670624 | 0.72 | PARP15 (0.40) | PARP10PARP2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054881-B1 | NOVEL SULFONAMIDE SUBSTITUTED CHROMAN DERIVATIVES USEFUL AS BETA-3 ADRENORECEPTOR AGONISTS | BAYER CORP (US) | 2008-07-30 | — | — | EP | disclosed |