Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6300711 | 1.00 | KMT2A (0.34) | KMT2AGBA1CDK1CCNB2CCNB1 | |
| SCHEMBL7717985 | 0.93 | FLT3 (0.31) | CDK1CCNB2CCNB1CCNA2CDK2 | |
| SCHEMBL526852 | 0.86 | KMT2A (0.36) | KMT2AGBA1CDK1CCNB2CCNB1 | |
| SCHEMBL9428560 | 0.85 | KMT2A (0.38) | KMT2AGBA1CDK1CCNB2CCNB1 | |
| SCHEMBL9428455 | 0.85 | KMT2A (0.38) | KMT2AGBA1CDK1CCNB2CCNB1 | |
| SCHEMBL9427851 | 0.81 | KMT2A (0.40) | KMT2AGBA1SLC29A1 | |
| SCHEMBL1231055 | 0.80 | TNKS2 (0.34) | — | |
| SCHEMBL9429384 | 0.80 | KMT2A (0.42) | KMT2AGBA1SLC29A1 | |
| SCHEMBL6300707 | 0.78 | HRH4 (0.33) | GBA1 | |
| SCHEMBL6299669 | 0.77 | KMT2A (0.36) | KMT2AGBA1SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6391949-B1 | — | — | None | — | — | US | disclosed |
| US-6872832-B2 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-03-29 | — | — | US | disclosed |
| US-6638997-B2 | Used for stabilizing polyolefin and automotive coating formulation against the deleterious effects of oxidative, thermal and actinic radiation | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-10-28 | — | — | US | disclosed |
| US-6586507-B2 | For stabilizing polyolefins, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation, also for stabilizing acid catalyzed and ambient cured coatings systems | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-07-01 | — | — | US | disclosed |
| US-20030120077-A1 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES PETER (US) | 2003-06-26 | — | — | US | disclosed |
| US-6420463-B1 | HEAT RESISTANCE, OXIDATION RESISTANCE OR PHOTOSTABILITY | CIBA SPECIALTY CHEMICALS CORP. | 2002-07-16 | — | — | US | disclosed |
| US-6420562-B2 | OXIDATION, HEAT AND RADIATION RESISTANCE | CIBA SPECIALITY CHEMICALS CORPORATION | 2002-07-16 | — | — | US | disclosed |
| US-6392041-B1 | OXIDATION, HEAT AND RADIATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-05-21 | — | — | US | disclosed |
| US-6391949-B2 | FOR AUTOMOBILE FINISHES; HEAT, OXIDATION, RADIATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-05-21 | — | — | US | disclosed |
| US-6388072-B2 | TETRAALKYL SUBSTITUTED PIPERIDINE SUBSTITUTED ON THE N-ATOM WITH O-E-OH GROUP (E= ALKYLENE OR PHENYLENE OR CYCLOALIPHATIC DERIVATIVES) ARE USED FOR STABILIZING POLYOLEFINS AND AUTOMOTIVE COATING AGAINST HEAT, OXIDATION | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-05-14 | — | — | US | disclosed |
| US-6380389-B2 | FOR POLYOLEFINS AND AUTOMOTIVE COATINGS; LIGHT, HEAT, OXIDATION RESISTANCE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-04-30 | — | — | US | disclosed |
| US-20020040145-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2002-04-04 | — | — | US | disclosed |
| US-20010031872-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-10-18 | — | — | US | disclosed |
| US-20010020099-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-09-06 | — | — | US | disclosed |
| US-20010018520-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-08-30 | — | — | US | disclosed |
| US-20010016658-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | GALBO JAMES P (US) | 2001-08-23 | — | — | US | disclosed |
| US-6271377-B1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040145-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | KMT2A 617/4885GBA1 1032/4885CDK1 3162/4885 |
| US-20010016658-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | KMT2A 617/4885GBA1 1032/4885CDK1 3162/4885 |
| US-20010020099-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | KMT2A 617/4885GBA1 1032/4885CDK1 3162/4885 |
| US-20030120077-A1 | Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith | OGG1, POLH, OGFOD1 | KMT2A 615/4885GBA1 1174/4885CDK1 2695/4885 |
| US-20010018520-A1 | Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | KMT2A 617/4885GBA1 1032/4885CDK1 3162/4885 |
| US-20010031872-A1 | Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith | POLH, OGG1, OGFOD1 | KMT2A 617/4885GBA1 1032/4885CDK1 3162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.