Sugi Predict

Sugi Predict / Compounds / SCHEMBL6533138

SCHEMBL6533138

SCHEMBL6533138

Nc1ccn(CCN2CCCCC2)n1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 1/20 0.41
▸ TERT O14746 1/20 0.41
▸ CYP1A2 P05177 2/20 0.40
▸ CYP2D6 P10635 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ ALDH1A1 P00352 4/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ SIGMAR1 Q99720 2/20 0.38
▸ HRH3 Q9Y5N1 2/20 0.38
▸ DRD2 P14416 2/20 0.38
▸ L3MBTL1 Q9Y468 3/20 0.37
▸ TDP1 Q9NUW8 2/20 0.37
▸ TSHR P16473 1/20 0.37
▸ DRD3 P35462 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6302885 0.98 ALDH1A1 (0.40) ALOX15TERTCYP1A2CYP2D6CYP2C19
SCHEMBL6304851 0.95 ALDH1A1 (0.40) ALOX15TERTCYP1A2CYP2D6CYP2C19
SCHEMBL6302511 0.90 HRH3 (0.41) ALOX15CYP1A2CYP3A4ALDH1A1MEN1
SCHEMBL6308796 0.88 EHMT2 (0.39) ALOX15ALDH1A1MEN1KMT2ASIGMAR1
SCHEMBL18235472 0.84 LMNA (0.42) ALDH1A1MEN1KMT2ASIGMAR1DRD2
SCHEMBL522026 0.84 NR5A2 (0.45) ALDH1A1MEN1KMT2ASIGMAR1
SCHEMBL6305135 0.84 ALDH1A1 (0.38) ALOX15ALDH1A1MEN1KMT2ASIGMAR1
SCHEMBL15553829 0.83 KDM1A (0.42) CYP3A4ALDH1A1MEN1KMT2ASIGMAR1
SCHEMBL18235388 0.83 KDM1A (0.42) ALOX15CYP2D6CYP3A4ALDH1A1MEN1
SCHEMBL18235299 0.83 ALDH1A1 (0.39) ALOX15CYP2D6CYP2C19CYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240400502-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME UNIV QUEENSLAND (AU) 2024-12-05 — — US disclosed
CN-113582889-B Sulfonylureas and related compounds and uses thereof 昆士兰大学 2024-09-20 — — CN disclosed
EP-3416948-B1 INDACENE BEARING SULFONYLUREAS AS ANTI-INFLAMMATORY AGENTS UNIV QUEENSLAND (AU) 2024-07-24 — — EP disclosed
US-11858922-B2 Sulfonylureas and related compounds and use of same THE UNIVERSITY OF QUEENSLAND (AU) 2024-01-02 — — US disclosed
US-11845715-B2 — — 2023-12-19 — — US disclosed
US-11845715-B2 — — 2023-12-19 — — US disclosed
US-11845715-B2 — — 2023-12-19 — — US disclosed
CN-109071454-B Sulfonylureas and related compounds and uses thereof 昆士兰大学 2023-02-17 — — CN disclosed
US-20220112159-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME UNIV QUEENSLAND (AU) 2022-04-14 — — US disclosed
CN-113582889-A Sulfonylureas and related compounds and uses thereof 昆士兰大学 2021-11-02 — — CN disclosed
US-20200299284-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME INFLAZOME LIMITED (IE) 2020-09-24 — — US disclosed
EP-3578547-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME The University of Queensland (AU) 2019-12-11 — — EP disclosed
EP-3578547-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME The University of Queensland (AU) 2019-12-11 — — EP disclosed
US-20180044287-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME INFLAZOME LIMITED (IE) 2018-02-15 — — US disclosed
US-20180044287-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME INFLAZOME LIMITED (IE) 2018-02-15 — — US disclosed
US-20180044287-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME INFLAZOME LIMITED (IE) 2018-02-15 — — US disclosed
EP-3259253-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME The University of Queensland (AU) 2017-12-27 — — EP disclosed
WO-2016131098-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME THE UNIVERSITY OF QUEENSLAND (AU) 2016-08-25 — — WO disclosed
WO-2016131098-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME THE UNIVERSITY OF QUEENSLAND (AU) 2016-08-25 — — WO disclosed
WO-2005051917-A9 PYRAZOLYL DERIVATIVES IN THE FORM OF DRUGS FOR TREATING ACUTE OR CHRONIC NEURONAL REGRESSIONS AVENTIS PHARMA SA (FR) 2005-09-29 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220112159-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME NLRP3, PYCARD, IAPP ALOX15 2371/4885TERT 4522/4885CYP1A2 4288/4885
US-11845715-B2 — NLRP3, PYCARD, NOD1 ALOX15 1575/4885TERT 4135/4885CYP1A2 4028/4885
US-20240400502-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME NLRP3, PYCARD, IAPP ALOX15 2371/4885TERT 4522/4885CYP1A2 4288/4885
US-11858922-B2 Sulfonylureas and related compounds and use of same NLRP3, NOD1, PYCARD ALOX15 369/4885TERT 4503/4885CYP1A2 878/4885
US-20180044287-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME NLRP3, PYCARD, IAPP ALOX15 2371/4885TERT 4522/4885CYP1A2 4288/4885
US-20200299284-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME NLRP3, NOD1, PYCARD ALOX15 369/4885TERT 4503/4885CYP1A2 878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.