Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306346 | 0.81 | GLP1R (0.40) | PIK3R1PIK3CAALDH1A1LMNAHPGD | |
| SCHEMBL2599803 | 0.65 | CTSL (0.53) | ALDH1A1LMNAHPGDHTTSMN1; SMN2 | |
| SCHEMBL6310836 | 0.61 | ALDH1A1 (0.44) | ALDH1A1LMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL6304431 | 0.61 | ALDH1A1 (0.44) | ALDH1A1LMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL2476180 | 0.60 | TNKS (0.46) | ALDH1A1LMNA | |
| SCHEMBL2599643 | 0.60 | ALDH1A1 (0.41) | ALDH1A1LMNACYP1A2CYP2C9HPGD | |
| SCHEMBL1954351 | 0.59 | ALDH1A1 (0.42) | ALDH1A1LMNACYP1A2HPGDSMN1; SMN2 | |
| SCHEMBL2474403 | 0.58 | PDE3B (0.45) | LMNACYP1A2CYP2C9HPGDCYP2C19 | |
| SCHEMBL3941247 | 0.58 | XDH (0.41) | LMNA | |
| SCHEMBL1631167 | 0.58 | PTGS2 (0.54) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6927214-B1 | Non-peptide GLP-1 agonists | NOVO NORDISK A/S (DK) | 2005-08-09 | — | — | US | disclosed |