Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.64 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.64 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HEXA | P06865 | 1/20 | 0.48 |
| ▸ | HEXB | P07686 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.46 |
| ▸ | TPH1 | P17752 | 2/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6314171 | 0.86 | NPC1 (0.72) | HSP90AA1HSP90AB1NPC1RAB9AKDM4E | |
| SCHEMBL27638920 | 0.83 | NPC1 (0.66) | HRH4NPC1RAB9AKDM4EPOLB | |
| SCHEMBL6309038 | 0.82 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1RAB9AKDM4EADORA2A | |
| SCHEMBL6310578 | 0.82 | HSP90AA1 (0.70) | HSP90AA1HSP90AB1HRH4NPC1RAB9A | |
| SCHEMBL6306895 | 0.81 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1NPC1RAB9AADORA2A | |
| SCHEMBL6309967 | 0.80 | HSP90AA1 (0.72) | HSP90AA1HSP90AB1HRH4NPC1RAB9A | |
| SCHEMBL4093530 | 0.78 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1HRH4NPC1RAB9A | |
| SCHEMBL6314388 | 0.76 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1HRH4NPC1RAB9A | |
| SCHEMBL6316030 | 0.76 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1NPC1KDM4EHEXA | |
| SCHEMBL30862210 | 0.73 | KIF11 (0.58) | HRH4DPP4KIF11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9895356-B2 | Methods and compositions for treating anxiety | HYDRA BIOSCIENCES, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-9895356-B2 | Methods and compositions for treating anxiety | HYDRA BIOSCIENCES, INC. (US) | 2018-02-20 | — | — | US | disclosed |
| US-20160220539-A1 | METHODS AND COMPOSITIONS FOR TREATING ANXIETY | HYDRA BIOSCIENCES, INC. | 2016-08-04 | — | — | US | disclosed |
| US-20160220539-A1 | METHODS AND COMPOSITIONS FOR TREATING ANXIETY | HYDRA BIOSCIENCES, INC. | 2016-08-04 | — | — | US | disclosed |
| US-9139573-B2 | Methods and compositions for treating anxiety | HYDRA BIOSCIENCES, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-9139573-B2 | Methods and compositions for treating anxiety | HYDRA BIOSCIENCES, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| US-8633233-B2 | Methods and compositions for treating anxiety | HYDRA BIOSCIENCES, INC. (US) | 2014-01-21 | — | — | US | disclosed |
| US-8633233-B2 | Methods and compositions for treating anxiety | HYDRA BIOSCIENCES, INC. (US) | 2014-01-21 | — | — | US | disclosed |
| US-20110319417-A1 | METHODS AND COMPOSITIONS FOR TREATING ANXIETY | HYDRA BIOSCIENCES, INC. | 2011-12-29 | — | — | US | disclosed |
| US-20110319417-A1 | METHODS AND COMPOSITIONS FOR TREATING ANXIETY | HYDRA BIOSCIENCES, INC. | 2011-12-29 | — | — | US | disclosed |
| US-6919339-B2 | ABCA-1 elevating compounds | CV THEAPEUTICS, INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20020128266-A1 | ABCA-1 elevating compounds | CV THERAPEUTICS, INC. | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110319417-A1 | METHODS AND COMPOSITIONS FOR TREATING ANXIETY | HTR5A, HTR2C, TRPC5 | HSP90AA1 1702/4885HSP90AB1 2178/4885HRH4 311/4885 |
| US-20160220539-A1 | METHODS AND COMPOSITIONS FOR TREATING ANXIETY | HTR5A, HTR2C, TRPC5 | HSP90AA1 1702/4885HSP90AB1 2178/4885HRH4 311/4885 |
| US-20020128266-A1 | ABCA-1 elevating compounds | ABCD3, ABCE1, ABCB4 | HSP90AA1 1676/4885HSP90AB1 1191/4885HRH4 4305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.