Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8816957 | 0.84 | CRHR1 (0.35) | PTGDR2CRHR1CCR2PPARG | |
| SCHEMBL6296496 | 0.82 | CFTR (0.44) | PTGDR2PPARG | |
| SCHEMBL6297199 | 0.79 | P2RX7 (0.35) | — | |
| SCHEMBL6293326 | 0.79 | DHODH (0.39) | PTGDR2CRHR1PPARG | |
| SCHEMBL29391001 | 0.74 | SLC6A9 (0.41) | CCR2 | |
| SCHEMBL6751338 | 0.74 | SLC6A9 (0.41) | CCR2 | |
| SCHEMBL5842222 | 0.73 | LIPC (0.40) | PTGDR2CRHR1 | |
| SCHEMBL8815743 | 0.71 | LIPC (0.42) | CRHR1CCR2 | |
| SCHEMBL9116989 | 0.69 | ALDH1A1 (0.38) | PTGDR2 | |
| SCHEMBL8489374 | 0.69 | CES2 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050079979-A1 | Substituted benzoylisoxazoles and the use thereof as herbicides | MULLER KLAUS-HELMUT (DE) | 2005-04-14 | — | — | US | disclosed |
| US-6838415-B1 | Substituted benzoylisoxazoles and the use thereof as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2005-01-04 | — | — | US | disclosed |
| EP-1178987-B1 | SUBSTITUTED BENZOYLISOXAZOLES AND THE USE THEREOF AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2003-08-13 | — | — | EP | disclosed |
| CN-1349532-A | Substituted benzoyl isoxazoles and their use as herbicides | BAYER AG (DE) | 2002-05-15 | — | — | CN | disclosed |
| EP-1178987-A1 | SUBSTITUTED BENZOYLISOXAZOLES AND THE USE THEREOF AS HERBICIDES | Bayer Aktiengesellschaft (DE) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000068227-A1 | SUBSTITUTED BENZOYLISOXAZOLES AND THE USE THEREOF AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050079979-A1 | Substituted benzoylisoxazoles and the use thereof as herbicides | CYP4X1, DDT, GLRX3 | PTGDR2 2150/4885CRHR1 1368/4885CCR2 2380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.