Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8138383 | 0.73 | GABRA1 (0.47) | GABRA1GABRB2CA2 | |
| SCHEMBL26190221 | 0.71 | CA2 (0.48) | GABRA1GABRB2CA2 | |
| SCHEMBL2365232 | 0.68 | CA2 (0.38) | GABRA1GABRB2CA2 | |
| SCHEMBL9696405 | 0.68 | CA2 (0.38) | GABRA1GABRB2CA2 | |
| SCHEMBL28041620 | 0.68 | CA2 (0.38) | GABRA1GABRB2CA2 | |
| SCHEMBL9696632 | 0.67 | CA2 (0.36) | GABRA1GABRB2CA2 | |
| Bromoethane SCHEMBL27514217 | 0.67 | ALDH1A1 (0.43) | GABRA1GABRB2CA2 | |
| SCHEMBL20047731 | 0.66 | CA2 (0.39) | GABRA1GABRB2CA2 | |
| SCHEMBL413809 | 0.65 | ALOX12 (0.36) | GABRA1GABRB2CA2 | |
| SCHEMBL9370172 | 0.65 | NR1H4 (0.39) | GABRA1GABRB2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844344-B2 | Benzofuran derivatives | ELI LILLY AND COMPANY (US) | 2005-01-18 | — | — | US | disclosed |
| US-20030232833-A1 | Benzofuran derivatives | ELI LILLY AND COMPANY | 2003-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232833-A1 | Benzofuran derivatives | BRD1, BPTF, HTR1F | GABRA1 55/4885GABRB2 25/4885CA2 4073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.