Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 7/20 | 0.40 |
| ▸ | KMO | O15229 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6313578 | 0.84 | HSD11B1 (0.49) | EGLN2HSD11B1IDO1ALDH1A1MAPT | |
| Benzene SCHEMBL27949779 | 0.81 | HSD11B1 (0.46) | EGLN2HSD11B1ALDH1A1MAPTNPC1 | |
| SCHEMBL6319050 | 0.75 | KMO (0.43) | EGLN2HSD11B1KMOIDO1GRM2 | |
| SCHEMBL10356476 | 0.75 | MAPK1 (0.42) | ALDH1A1MAPT | |
| SCHEMBL24409170 | 0.74 | PKM (0.50) | KMOMAPT | |
| SCHEMBL8486970 | 0.72 | HSD11B1 (0.44) | EGLN2HSD11B1ALDH1A1MAPTNPC1 | |
| SCHEMBL24409169 | 0.72 | PTGDR2 (0.38) | EGLN2KMO | |
| SCHEMBL24425235 | 0.72 | EGFR (0.39) | MAPT | |
| SCHEMBL7707702 | 0.71 | KMO (0.42) | EGLN2HSD11B1KMOGRM2BCHE | |
| SCHEMBL2342660 | 0.71 | PSEN1 (0.43) | ARMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6897322-B2 | Method of producing 1-alkyl-3-aryl-5-difluoromethoxy-1H-pyrazoles | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-24 | — | — | US | disclosed |
| US-20040059128-A1 | Method of producing 1-alkyl-3-aryl-5-difluoromethoxy-ih-pyrazoles | BASF AKTIENGESELLSCHAFT (DE) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040059128-A1 | Method of producing 1-alkyl-3-aryl-5-difluoromethoxy-ih-pyrazoles | CYP2E1, CYP2F1, CYP1A1 | EGLN2 341/4885HSD11B1 77/4885ESR1 3337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.