Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.60 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6309423 | 0.91 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1CYP2D6DHFRMAOB | |
| SCHEMBL6307180 | 0.81 | HSP90AA1 (0.57) | HSP90AA1HSP90AB1DHFRPPARGADORA2A | |
| Hydrochloric Acid SCHEMBL30496698 | 0.81 | MAOB (0.54) | CYP2D6DHFRMAOAMAOBMPO | |
| SCHEMBL6315112 | 0.77 | HSP90AA1 (0.52) | HSP90AA1HSP90AB1DHFRPPARGADORA2A | |
| SCHEMBL6315317 | 0.76 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1ADORA2AADORA1 | |
| SCHEMBL6315250 | 0.75 | NPC1 (0.71) | HSP90AA1HSP90AB1 | |
| SCHEMBL28088281 | 0.74 | HPGD (0.49) | CYP2D6DHFRMPOADORA2AADORA1 | |
| SCHEMBL28924736 | 0.72 | CASP1 (0.64) | CYP2D6DHFRMAOAMAOBADORA2A | |
| SCHEMBL10916421 | 0.70 | HSP90AA1 (0.61) | HSP90AA1HSP90AB1DHFRADORA2AADORA1 | |
| SCHEMBL4093530 | 0.69 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6919339-B2 | ABCA-1 elevating compounds | CV THEAPEUTICS, INC. (US) | 2005-07-19 | — | — | US | disclosed |
| US-20020128266-A1 | ABCA-1 elevating compounds | CV THERAPEUTICS, INC. | 2002-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128266-A1 | ABCA-1 elevating compounds | ABCD3, ABCE1, ABCB4 | HSP90AA1 1676/4885HSP90AB1 1191/4885CYP2D6 1350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.