Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 12/20 | 0.41 |
| ▸ | KDR | P35968 | 5/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6316756 | 0.71 | KDR (0.40) | TRPV1KDRNOTUMRAB9ALMNA | |
| SCHEMBL6316148 | 0.69 | LMNA (0.41) | TRPV1KDRNOTUMRAB9ALMNA | |
| SCHEMBL11967083 | 0.66 | TRPA1 (0.57) | TRPV1KDRRAB9ALMNAHSD17B10 | |
| SCHEMBL11895395 | 0.66 | TRPA1 (0.57) | TRPV1KDRRAB9ALMNAHSD17B10 | |
| SCHEMBL11954715 | 0.66 | TRPA1 (0.57) | TRPV1KDRRAB9ALMNAHSD17B10 | |
| Butylcyclohexane SCHEMBL846898 | 0.62 | TRPV1 (0.56) | TRPV1KDRNOTUMRAB9ALMNA | |
| SCHEMBL846245 | 0.59 | TRPV1 (0.56) | TRPV1KDRNOTUMRAB9ALMNA | |
| SCHEMBL846447 | 0.59 | TRPV1 (1.00) | TRPV1KDRRAB9AKDM4ENPC1 | |
| SCHEMBL845960 | 0.59 | TRPV1 (0.98) | TRPV1KDRRAB9AKDM4ENPC1 | |
| SCHEMBL845842 | 0.58 | TRPV1 (0.80) | TRPV1KDRRAB9AHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | APOB, LDLR, LPL | TRPV1 3036/4885KDR 2530/4885NOTUM 3343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.