Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 7/20 | 0.44 |
| ▸ | HTR1B | P28222 | 4/20 | 0.41 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717077 | 0.87 | ADRA2C (0.46) | HTR1DHTR1BHTR6TAAR1ADRA2A | |
| SCHEMBL4717682 | 0.87 | ADRA1A (0.46) | HTR1DHTR1BHTR6TAAR1ADRA2A | |
| SCHEMBL4722295 | 0.85 | ADRA2A (0.47) | HTR1DHTR1BHTR6TAAR1ADRA2A | |
| SCHEMBL4717753 | 0.84 | HTR6 (0.53) | HTR1DHTR6TAAR1ADRA2AADRA2C | |
| SCHEMBL4717770 | 0.83 | HTR1D (0.38) | HTR1DHTR1BTAAR1ADRA2AADRA2C | |
| SCHEMBL4717783 | 0.80 | ADRA2C (0.46) | HTR1DHTR1BHTR6TAAR1ADRA2A | |
| SCHEMBL4717081 | 0.80 | ADRA2A (0.46) | HTR1DHTR1BHTR6TAAR1ADRA2A | |
| SCHEMBL4721369 | 0.79 | TAAR1 (0.45) | HTR1DHTR1BTAAR1ADRA2AADRA2C | |
| SCHEMBL4720414 | 0.75 | TAAR1 (0.45) | HTR1DHTR1BHTR6TAAR1ADRA2A | |
| SCHEMBL4717265 | 0.74 | TAAR1 (0.50) | HTR1DHTR1BTAAR1ADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6979696-B2 | Method for detecting a gram-negative bacterial autoinducer molecule | ROCHE PALO ALTO LLC (US) | 2005-12-27 | — | — | US | disclosed |
| US-20040224973-A1 | Substituted indoles as alpha-1 agonists | ROCHE PALO ALTO LLC | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224973-A1 | Substituted indoles as alpha-1 agonists | ADRA1A, ADRB1, ADRA1D | HTR1D 12/4885HTR1B 34/4885HTR6 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.