Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | SOD1 | P00441 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320250 | 0.88 | MAPT (0.58) | ALDH1A1LMNAHPGDKDM4EHTT | |
| SCHEMBL6320455 | 0.87 | FKBP1A (0.61) | ALDH1A1LMNAHPGDENPP2MAPK1 | |
| SCHEMBL6325847 | 0.81 | MAPT (0.64) | LMNAKDM4EGSK3BSMN1; SMN2MAPT | |
| SCHEMBL14982082 | 0.78 | MAPT (0.65) | ALDH1A1LMNAHPGDKDM4EHTT | |
| SCHEMBL22221525 | 0.76 | ALDH1A1 (1.00) | ALDH1A1LMNAHPGDKDM4EHTT | |
| SCHEMBL3868073 | 0.75 | MAPT (0.63) | LMNAKDM4EMAPT | |
| SCHEMBL27608865 | 0.75 | FAAH (0.53) | LMNAHPGDENPP2MAPK1GSK3B | |
| SCHEMBL21690 | 0.74 | MAPT (0.66) | ALDH1A1LMNAHPGDKDM4EHTT | |
| SCHEMBL6321338 | 0.74 | MAPT (0.64) | ALDH1A1LMNAHPGDKDM4EHTT | |
| SCHEMBL6319805 | 0.74 | MAPT (0.68) | ALDH1A1LMNAKDM4EHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |