Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 6/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 4/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | BCL6 | P41182 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325709 | 0.89 | PTK2 (0.37) | TDP2CDK2CDC7CCNE1DBF4 | |
| SCHEMBL6317759 | 0.84 | OPRM1 (0.38) | TDP2CDK2CDC7CCNE1DBF4 | |
| SCHEMBL6324395 | 0.83 | BRD4 (0.35) | TDP2CDK2CDC7CCNE1DBF4 | |
| SCHEMBL6319893 | 0.82 | PTK2 (0.35) | TDP2CDK2CDC7CCNE1DBF4 | |
| SCHEMBL6317290 | 0.81 | FGFR1 (0.35) | TDP2PTK2PTK2BJAK3IRAK4 | |
| SCHEMBL6325319 | 0.76 | KDR (0.44) | KDM4ENPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL6325622 | 0.70 | EPHX2 (0.34) | CDK2CDC7CCNE1DBF4PTK2 | |
| SCHEMBL6320162 | 0.69 | PTK2 (0.35) | TDP2CDK2CDC7CCNE1DBF4 | |
| SCHEMBL6325348 | 0.68 | GRIA1 (0.32) | CDK2CDC7CCNE1DBF4PTK2 | |
| SCHEMBL6320139 | 0.68 | ALPL (0.40) | KDM4ENPC1SMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | APOB, LDLR, LPL | TDP2 3606/4885CDK2 1197/4885CDC7 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.