Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.33 |
| ▸ | BCL6 | P41182 | 2/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6319893 | 0.84 | PTK2 (0.35) | FGFR1FGFR2FGFR3PTK2TDP2 | |
| SCHEMBL6325709 | 0.84 | PTK2 (0.37) | FGFR1FGFR2FGFR3PTK2TDP2 | |
| SCHEMBL6324395 | 0.83 | BRD4 (0.35) | PTK2TDP2OPRD1BRD4CREBBP | |
| SCHEMBL6320852 | 0.81 | TDP2 (0.37) | FGFR1FGFR2FGFR3PTK2TDP2 | |
| SCHEMBL6317759 | 0.70 | OPRM1 (0.38) | PTK2TDP2OPRD1BCL6PTK2B | |
| SCHEMBL6256396 | 0.65 | EPHX2 (0.32) | OPRD1SMYD3 | |
| SCHEMBL6317771 | 0.65 | LMNA (0.48) | MEN1KMT2A | |
| SCHEMBL6320162 | 0.64 | PTK2 (0.35) | PTK2TDP2BRD4CREBBPPTK2B | |
| SCHEMBL6323006 | 0.62 | PDE3B (0.33) | PTK2OPRD1SMYD3 | |
| SCHEMBL6317954 | 0.62 | PKM (0.33) | PTK2OPRD1SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | claimed |
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | APOB, LDLR, LPL | FGFR1 1675/4885FGFR2 3523/4885FGFR3 3122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.