Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 5/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320852 | 0.69 | TDP2 (0.37) | PTK2TDP2IRAK4JAK3RAB9A | |
| SCHEMBL6317759 | 0.68 | OPRM1 (0.38) | PTK2TDP2IRAK4JAK3RAB9A | |
| SCHEMBL6325709 | 0.68 | PTK2 (0.37) | PTK2TDP2IRAK4JAK3RAB9A | |
| SCHEMBL6324395 | 0.66 | BRD4 (0.35) | PTK2TDP2IRAK4JAK3HDAC6 | |
| SCHEMBL6319893 | 0.65 | PTK2 (0.35) | PTK2TDP2IRAK4JAK3RAB9A | |
| SCHEMBL6317290 | 0.64 | FGFR1 (0.35) | PTK2TDP2IRAK4JAK3PTK2B | |
| SCHEMBL6325670 | 0.62 | KDR (0.38) | RAB9ALMNAPOLBHSD17B10RPS6KA3 | |
| SCHEMBL6317821 | 0.62 | KDR (0.39) | RAB9ALMNAPOLBTSHRHSD17B10 | |
| SCHEMBL6317753 | 0.61 | IGF1R (0.58) | PTK2CDK2KDRPTK2B | |
| SCHEMBL6319622 | 0.61 | KDM4E (0.44) | RAB9ALMNANPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | claimed |
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | QUATRX PHARMACEUTICALS CO. | 2005-06-30 | — | — | US | disclosed |
| US-20050101675-A1 | Benzamidine derivatives and process for production thereof | TEIJIN LIMITED (JP) | 2005-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143349-A1 | Phosphorus containing compounds useful for the regulation of LDL and Lp(a) levels | APOB, LDLR, LPL | PTK2 1567/4885TDP2 3606/4885IRAK4 3405/4885 |
| US-20050101675-A1 | Benzamidine derivatives and process for production thereof | AOC2, TALDO1, AOC1 | PTK2 4500/4885TDP2 4582/4885IRAK4 4378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.