SCHEMBL6322676

SCHEMBL6322676

CC(C)(C)OC(=O)N1C(=O)C2=C(c3ccc(Cl)cc3)N(C(=O)OC(C)(C)C)C(=O)C2=C1c1ccc(Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
STS P08842 2/20 0.40
BCHE P06276 1/20 0.39
VEGFA P15692 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MT-CO2 P00403 1/20 0.34
KCNK3 O14649 1/20 0.34
KCNK9 Q9NPC2 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C19 P33261 1/20 0.34
PPARA Q07869 1/20 0.34
GAA P10253 1/20 0.34
PTPN2 P17706 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7755310 0.95 KMT2A (0.40) MEN1KMT2ASTSBCHESMN1; SMN2
SCHEMBL7754292 0.88 CNR1 (0.39) MEN1KMT2ABCHEHTTMAPT
SCHEMBL24565414 0.87 BCHE (0.40) STSBCHEMAPTPTPN2PTPN1
SCHEMBL8949810 0.87 GPR119 (0.40) MEN1KMT2ABCHESMN1; SMN2NPSR1
SCHEMBL7946813 0.85 HSD11B1 (0.40) BCHEHTTSMN1; SMN2MAPTPTPN2
SCHEMBL14403040 0.85 MEN1 (0.34) MEN1KMT2ABCHECYP1A2CYP3A4
SCHEMBL13461001 0.85 ELANE (0.35) MEN1KMT2ASTSCYP1A2CYP3A4
SCHEMBL902929 0.85 BCHE (0.48) BCHE
SCHEMBL8069949 0.83 XPO1 (0.43) MEN1KMT2ASTSBCHESMN1; SMN2
SCHEMBL12393911 0.82 GPR119 (0.41) BCHEGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050148690-A1 Coloring composition ICHIMURA KUNIHIRO (JP) 2005-07-07 US claimed
EP-2169010-A2 Method of producing organic pigment fine-particles, organic pigment fine-particles obtained thereby, liquid dispersion thereof, and composition thereof FUJIFILM Corporation (JP) 2010-03-31 EP disclosed
EP-1840172-A2 Method of producing organic pigment fine-particles, and organic pigment fine-particles obtained thereby and liquid dispersion of the same FUJIFILM Corporation (JP) 2007-10-03 EP disclosed
EP-0975697-B1 THIAZINE INDIGO PIGMENTS, SOLID SOLUTIONS THEREOF AND THEIR PREPARATION CLARIANT FINANCE BVI LTD (VG) 2003-04-16 EP disclosed
US-6200378-B1 Thiazine indigo pigments, solid solutions thereof and their preparation CLARIANT FINANCE (BVIø) LIMITED (VG) 2001-03-13 US disclosed
EP-0975697-A1 THIAZINE INDIGO PIGMENTS, SOLID SOLUTIONS THEREOF AND THEIR PREPARATION Clariant Finance (BVI) Limited (VG) 2000-02-02 EP disclosed
WO-1998032800-A1 THIAZINE INDIGO PIGMENTS, SOLID SOLUTIONS THEREOF AND THEIR PREPARATION CLARIANT FINANCE (BVI) LIMITED (VG) 1998-07-30 WO disclosed