Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6322676 | 0.95 | MEN1 (0.43) | KMT2AMEN1STSBCHEMAPT | |
| SCHEMBL8949810 | 0.93 | GPR119 (0.40) | KMT2AMEN1TP53GPR119BCHE | |
| SCHEMBL7754292 | 0.88 | CNR1 (0.39) | KMT2AMEN1TP53GPR119BCHE | |
| SCHEMBL24565414 | 0.82 | BCHE (0.40) | STSGPR119BCHEMAPTLMNA | |
| SCHEMBL7946813 | 0.81 | HSD11B1 (0.40) | BCHEMAPTTDP1SMN1; SMN2 | |
| SCHEMBL14403040 | 0.81 | MEN1 (0.34) | KMT2AMEN1BCHEMAPTCYP2C19 | |
| SCHEMBL13461001 | 0.81 | ELANE (0.35) | KMT2AMEN1STSMAPTCYP2C19 | |
| SCHEMBL902929 | 0.80 | BCHE (0.48) | GPR119BCHETDP1HSD17B10 | |
| SCHEMBL8069949 | 0.79 | XPO1 (0.43) | KMT2AMEN1STSBCHECNR2 | |
| SCHEMBL12393911 | 0.78 | GPR119 (0.41) | GPR119BCHEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765919-B1 | Monophasic solid solutions with asymmetrical pyrrolo-(4-3-c)-pyrroles as host | CIBA SC HOLDING AG (CH) | 2001-02-21 | — | — | EP | disclosed |
| US-5756746-A | KETOPYRROLES AND QUINACRIDONES FOR LIGHT STABLE AND WEATHER RESISTANT COLOR COMPOSITIONS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0765919-A2 | Monophasic solid solutions with asymmetrical pyrrolo-(4-3-c)-pyrroles as host | Ciba SC Holding AG (CH) | 1997-04-02 | — | — | EP | disclosed |