Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.35 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.35 |
| ▸ | CACNB3 | P54284 | 2/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.35 |
| ▸ | CACNG7 | P62955 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8053167 | 0.92 | GPR119 (0.42) | GPR119KAT6AKAT5MAPTBCHE | |
| SCHEMBL7755310 | 0.88 | KMT2A (0.40) | CNR1GPR119MEN1KMT2ATP53 | |
| SCHEMBL6322676 | 0.88 | MEN1 (0.43) | MEN1KMT2AMAPTBCHEHTT | |
| SCHEMBL8069949 | 0.86 | XPO1 (0.43) | MEN1KMT2ABCHE | |
| SCHEMBL8949810 | 0.81 | GPR119 (0.40) | GPR119MEN1KMT2ATP53MAPT | |
| SCHEMBL902929 | 0.80 | BCHE (0.48) | GPR119BCHETDP1ALDH1A1 | |
| SCHEMBL24565414 | 0.76 | BCHE (0.40) | GPR119MAPTBCHELMNAALDH1A1 | |
| SCHEMBL7900611 | 0.76 | BCHE (0.42) | GPR119MEN1KMT2AMAPTBCHE | |
| SCHEMBL7946813 | 0.75 | HSD11B1 (0.40) | MAPTBCHEHTTTDP1L3MBTL1 | |
| SCHEMBL14403040 | 0.75 | MEN1 (0.34) | CNR1MEN1KMT2AMAPTBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765919-B1 | Monophasic solid solutions with asymmetrical pyrrolo-(4-3-c)-pyrroles as host | CIBA SC HOLDING AG (CH) | 2001-02-21 | — | — | EP | disclosed |
| US-5756746-A | KETOPYRROLES AND QUINACRIDONES FOR LIGHT STABLE AND WEATHER RESISTANT COLOR COMPOSITIONS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| EP-0765919-A2 | Monophasic solid solutions with asymmetrical pyrrolo-(4-3-c)-pyrroles as host | Ciba SC Holding AG (CH) | 1997-04-02 | — | — | EP | disclosed |