Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 4/20 | 0.57 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6323761 | 0.96 | L3MBTL1 (0.52) | THRATHRBPLA2G4APPARAKDM4E | |
| SCHEMBL6322900 | 0.82 | L3MBTL1 (0.63) | THRATHRBPLA2G4ALMNAMAPT | |
| SCHEMBL6325847 | 0.82 | MAPT (0.64) | KDM4ELMNAMAPTL3MBTL1RAB9A | |
| SCHEMBL1284112 | 0.82 | L3MBTL1 (0.59) | THRATHRBL3MBTL1 | |
| SCHEMBL6202777 | 0.81 | MAPT (0.64) | KDM4ELMNAMAPTL3MBTL1RAB9A | |
| SCHEMBL29430540 | 0.81 | THRB (0.57) | THRATHRBPPARAKDM4ELMNA | |
| SCHEMBL1283890 | 0.80 | L3MBTL1 (0.61) | THRATHRBPPARALMNAMAPT | |
| SCHEMBL12611881 | 0.80 | PLA2G4A (0.56) | THRATHRBPLA2G4ALMNAMEN1 | |
| SCHEMBL11001416 | 0.80 | PPARA (0.58) | THRATHRBPPARALMNAMAPT | |
| SCHEMBL29430571 | 0.80 | PPARA (0.58) | THRATHRBPPARALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |