Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.63 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | THRA | P10827 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6323761 | 0.86 | L3MBTL1 (0.52) | L3MBTL1LMNAPLA2G4ARAB9AMAOB | |
| SCHEMBL6327817 | 0.83 | LMNA (0.73) | L3MBTL1LMNAMAPK1CASP3SENP7 | |
| SCHEMBL6322708 | 0.82 | THRA (0.57) | L3MBTL1LMNAPLA2G4ARAB9AMAOB | |
| SCHEMBL7637309 | 0.80 | MMP1 (0.58) | L3MBTL1LMNARAB9ATHRATHRB | |
| SCHEMBL11488970 | 0.79 | MAPT (0.64) | L3MBTL1LMNAMAPK1CASP3SENP7 | |
| SCHEMBL11847871 | 0.79 | LMNA (0.64) | L3MBTL1LMNAMAPK1CASP3SENP7 | |
| SCHEMBL6318784 | 0.79 | MAPT (0.64) | L3MBTL1LMNAMAPK1CASP3SENP7 | |
| SCHEMBL11044041 | 0.79 | RARB (0.57) | LMNAHTR7THRATHRB | |
| SCHEMBL7637316 | 0.78 | NPC1 (0.59) | L3MBTL1LMNARAB9ATHRATHRB | |
| SCHEMBL10708129 | 0.78 | THRB (0.55) | FAAHTHRATHRBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |