Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6327472 | 0.80 | LMNA (0.37) | LMNA | |
| SCHEMBL6328252 | 0.76 | LMNA (0.33) | LMNA | |
| SCHEMBL11269568 | 0.76 | TSHR (0.40) | TSHRPTPN1MEN1KMT2ALMNA | |
| SCHEMBL197338 | 0.76 | ALDH1A1 (0.33) | TSHR | |
| SCHEMBL12158579 | 0.73 | — | — | |
| SCHEMBL457731 | 0.72 | PKM (0.40) | MEN1KMT2ALMNA | |
| SCHEMBL826905 | 0.72 | TSHR (0.46) | TSHRPTPN1MEN1KMT2ALMNA | |
| SCHEMBL7406644 | 0.71 | PKM (0.39) | MEN1KMT2ALMNA | |
| Water SCHEMBL10546251 | 0.71 | MEN1 (0.40) | MEN1KMT2ALMNA | |
| SCHEMBL12128600 | 0.70 | TSHR (0.43) | TSHRPTPN1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115466212-B | 2-trifluoromethyl quinoline compound and synthetic method and application thereof | 河南农业大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-115466212-A | 2-trifluoromethyl quinoline compound and synthetic method and application thereof | 河南农业大学 | 2022-12-13 | — | — | CN | disclosed |
| US-6893861-B1 | Method for producing trifluoro-3(r)-hydroxybutyric acid derivatives | LONZA AG (CH) | 2005-05-17 | — | — | US | disclosed |