SCHEMBL6327472

SCHEMBL6327472

CCOC(C)OC(=O)C(F)(F)C(=O)CF

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6328252 0.92 LMNA (0.33) LMNA
SCHEMBL6323017 0.80 TSHR (0.36) LMNA
SCHEMBL785931 0.74 LMNA (0.46) LMNA
SCHEMBL457731 0.74 PKM (0.40) LMNA
SCHEMBL10259014 0.72 LMNA (0.37) LMNA
SCHEMBL10693911 0.72 LMNA (0.44) LMNA
SCHEMBL7406644 0.72 PKM (0.39) LMNA
Water SCHEMBL10546251 0.72 MEN1 (0.40) LMNA
SCHEMBL47442 0.71 LMNA (0.42) LMNA
SCHEMBL10098354 0.71 LMNA (0.42) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6893861-B1 Method for producing trifluoro-3(r)-hydroxybutyric acid derivatives LONZA AG (CH) 2005-05-17 US disclosed