Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Trifluoroacetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.35 |
| ▸ | ACLY | P53396 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL585598 | 1.00 | — | — | |
| Trifluoroacetic Acid SCHEMBL8820428 | 0.96 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1THRBTSHRTP53 | |
| Trifluoroacetic Acid SCHEMBL21802705 | 0.96 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1THRBTSHRTP53 | |
| Trifluoroacetic Acid SCHEMBL11213859 | 0.96 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1THRBTSHRTP53 | |
| Trifluoroacetic Acid SCHEMBL11147435 | 0.96 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1THRBTSHRTP53 | |
| Trifluoroacetic Acid SCHEMBL216376 | 0.96 | — | — | |
| Trifluoroacetic Acid SCHEMBL96736 | 0.96 | — | — | |
| Trifluoroacetic Acid SCHEMBL4962364 | 0.96 | — | — | |
| Trifluoroacetic Acid SCHEMBL4651002 | 0.96 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1THRBTSHRTP53 | |
| Trifluoroacetic Acid SCHEMBL6371617 | 0.96 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1THRBTSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004900-A | LiErF4Up-conversion nano luminescent material with base core-shell structure and preparation method thereof | 吉林大学 | 2021-06-22 | — | — | CN | disclosed |
| EP-1560228-B1 | COMPOSITION FOR THICK OXIDE SUPERCONDUCTOR FILM AND OXIDE SUPERCONDUCTOR IN FORM OF THICK FILM TAPE | INT SUPERCONDUCTIVITY TECH (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-7307046-B2 | Composition for thick oxide superconductor film and method of producing oxide superconductor in form of thick film tape using the same | INTERNATIONAL SUPERCONDUCTIVITY TECHNOLOGY CENTER, THE JURIDICAL FOUNDATION (JP) | 2007-12-11 | — | — | US | disclosed |
| US-20060043347-A1 | Composition for thick oxide superconductor film and oxide superconductor in form of thick film tape | SWCC CORPORATION (JP) | 2006-03-02 | — | — | US | disclosed |
| EP-1560228-A1 | COMPOSITION FOR THICK OXIDE SUPERCONDUCTOR FILM AND OXIDE SUPERCONDUCTOR IN FORM OF THICK FILM TAPE | International Superconductivity Technology Center, The Juridical Foundation (JP) | 2005-08-03 | — | — | EP | disclosed |