Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6332537 | 0.94 | STK39 (0.55) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL6323898 | 0.92 | NPC1 (0.49) | RAB9ANPC1GAAKDM4EHTT | |
| SCHEMBL6324404 | 0.91 | CBS (0.54) | RAB9ANPC1GAAKDM4EHTT | |
| SCHEMBL6326802 | 0.91 | MAPT (0.55) | RAB9ANPC1KDM4EHTTMCL1 | |
| SCHEMBL6327276 | 0.91 | LMNA (0.50) | RAB9ANPC1GAAKDM4EHTT | |
| SCHEMBL6324687 | 0.90 | HTT (0.47) | RAB9ANPC1GAAKDM4EHTT | |
| SCHEMBL6323345 | 0.88 | RAB9A (0.50) | RAB9ANPC1GAAKDM4EHTT | |
| SCHEMBL6445760 | 0.88 | CSNK2A2 (0.52) | RAB9ANPC1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL6447053 | 0.88 | CSNK2A2 (0.49) | RAB9ANPC1KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL6322366 | 0.87 | KMT2A (0.49) | RAB9ANPC1KDM4EHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124664-A1 | Urea thiadiazole inhibitors of plasminogen activator inhibior-1 | BRISTOL-MYERS SQUIBB CO. | 2005-06-09 | — | — | US | claimed |
| US-20050124664-A1 | Urea thiadiazole inhibitors of plasminogen activator inhibior-1 | BRISTOL-MYERS SQUIBB CO. | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124664-A1 | Urea thiadiazole inhibitors of plasminogen activator inhibior-1 | SERPINE1, SERPINC1, SERPINB1 | RAB9A 3129/4885NPC1 2401/4885GAA 2065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.