Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 9/20 | 0.42 |
| ▸ | ACE | P12821 | 7/20 | 0.42 |
| ▸ | CPA1 | P15085 | 6/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6324685 | 0.88 | ALDH1A1 (0.49) | ALDH1A1MAPTMMEACECPA1 | |
| SCHEMBL6319028 | 0.88 | ALDH1A1 (0.49) | ALDH1A1MAPTMMEACECPA1 | |
| SCHEMBL6319021 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPTMMEACECPA1 | |
| SCHEMBL6317068 | 0.85 | REN (0.46) | ALDH1A1MAPTMMEACECPA1 | |
| SCHEMBL6319195 | 0.82 | GHSR (0.46) | ALDH1A1MAPTMMEACECPA1 | |
| SCHEMBL7161014 | 0.82 | GHSR (0.46) | ALDH1A1MAPTMMEACECPA1 | |
| SCHEMBL7063341 | 0.82 | ALDH1A1 (0.44) | ALDH1A1MAPTMMEACEMMP2 | |
| SCHEMBL6321057 | 0.82 | BACE1 (0.43) | ALDH1A1MAPTHDAC1 | |
| SCHEMBL6318120 | 0.82 | HRH4 (0.45) | MMEACECPA1ACE2MMP2 | |
| SCHEMBL6320709 | 0.80 | CYP1A2 (0.39) | ALDH1A1MAPTMMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055261-A1 | Compounds with growth hormone releasing properties | HELSINN THERAPEUTICS (U.S.), INC. | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055261-A1 | Compounds with growth hormone releasing properties | GHRHR, GHSR, IGFBP1 | ALDH1A1 2804/4885MAPT 4183/4885MME 712/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.