Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6324712 | 0.86 | HSD17B10 (0.40) | CBFBTDP1MAOADYRK1AHSD17B10 | |
| SCHEMBL9305459 | 0.82 | ALDH1A1 (0.44) | CBFBALDH1A1ALOX15RAD52UBE2N | |
| SCHEMBL10707113 | 0.79 | TUBB4A (0.45) | ALDH1A1ALOX15RAD52UBE2NS1PR4 | |
| SCHEMBL6467818 | 0.79 | CBFB (0.52) | CBFBALDH1A1ALOX15TDP1RAD52 | |
| SCHEMBL4226862 | 0.79 | ALDH1A1 (0.56) | CBFBALDH1A1ALOX15TDP1MAOA | |
| SCHEMBL727388 | 0.79 | PLAU (0.61) | CBFBALDH1A1ALOX15TDP1RAD52 | |
| SCHEMBL17309628 | 0.78 | ALDH1A1 (0.41) | CBFBALDH1A1ALOX15RAD52UBE2N | |
| SCHEMBL8083831 | 0.77 | TUBB4A (0.55) | S1PR4S1PR1S1PR5TSHR | |
| SCHEMBL14557086 | 0.76 | S1PR4 (0.45) | ALDH1A1ALOX15TDP1RAD52UBE2N | |
| SCHEMBL13438570 | 0.76 | SLC2A1 (0.42) | CBFBALDH1A1ALOX15RAD52UBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180203353-A1 | CURED FILM AND METHOD FOR MANUFACTURING SAME | TORAY INDUSTRIES, INC. (JP) | 2018-07-19 | — | — | US | disclosed |
| US-20180066107-A1 | PHOTOSENSITIVE RESIN COMPOSITION | TORAY INDUSTRIES, INC. (JP) | 2018-03-08 | — | — | US | disclosed |
| CN-1642941-A | 1-N-aminobenzimidazole derivatives | ZERIA PHARM CO LTD (JP) | 2005-07-20 | — | — | CN | disclosed |
| US-20050148634-A1 | 1-N-Aminobenzimidazole derivatives | ZERIA PHARMACEUTICAL CO., LTD (JP) | 2005-07-07 | — | — | US | disclosed |
| US-6906078-B2 | Method of using (H+/K+) ATPase inhibitors as antiviral agents | PHARMACIA CORPORATION (US) | 2005-06-14 | — | — | US | disclosed |
| US-6642264-B1 | Thiazolo(3,2-a)benzoimidazole derivatives act specifically on metabotropic glutamate receptors and are used as medicaments. | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| CN-1120842-C | New thiazole benzimidazole derivative | YAMANOUCHI PHARMA CO LTD (JP) | 2003-09-10 | — | — | CN | disclosed |
| EP-1167369-A1 | NOVEL THIAZOLOBENZIMIDAZOLE DERIVATIVES | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2002-01-02 | — | — | EP | disclosed |
| US-20010047038-A1 | Method of using (H+/K+) ATPase inhibitors as antiviral agents | MOORMAN ALAN E (US) | 2001-11-29 | — | — | US | disclosed |
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |
| CN-1271731-A | New thiazole benzimidazole derivative | YAMANOUCHI PHARMA CO LTD (JP) | 2000-11-01 | — | — | CN | disclosed |
| US-5945425-A | ADENOSINE TRIPHOSPHASE INHIBITOR; DNA VIRICIDE | G.D. SEARLE & CO. (US) | 1999-08-31 | — | — | US | disclosed |
| EP-0457331-B1 | Piperidine derivatives and antiulcer composition containing the same | MEIJI SEIKA KAISHA (JP) | 1996-11-20 | — | — | EP | disclosed |
| WO-1995029897-A1 | METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS | G.D. SEARLE & CO. (US) | 1995-11-09 | — | — | WO | disclosed |
| US-5185347-A | PIPERIDINE COMPOUNDS AND ANTIULCER COMPOSITION CONTAINING THE SAME | MEIJI SEIKA KAISHA LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| EP-0457331-A1 | Piperidine derivatives and antiulcer composition containing the same | MEIJI SEIKA KAISHA LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |
| US-4772619-A | ANTIULCER AGENTS | G. D. SEARLE & CO. (US) | 1988-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148634-A1 | 1-N-Aminobenzimidazole derivatives | CYP1B1, CYP2E1, CYP1A1 | CBFB 755/4885ALDH1A1 57/4885ALOX15 283/4885 |
| US-20010047038-A1 | Method of using (H+/K+) ATPase inhibitors as antiviral agents | ATP4A, ATP1A1, ATP1A4 | CBFB 2862/4885ALDH1A1 2148/4885ALOX15 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.