SCHEMBL6324712

SCHEMBL6324712

OCc1ccc2[nH]c(S)nc2c1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.40
CBFB Q13951 6/20 0.39
MAOA P21397 1/20 0.35
DYRK1A Q13627 1/20 0.35
TYMS P04818 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ILK Q13418 1/20 0.33
RIPK1 Q13546 1/20 0.33
MAP2K4 P45985 1/20 0.33
RHEB Q15382 1/20 0.32
PARP1 P09874 1/20 0.32
RECQL P46063 1/20 0.32
BRAF P15056 1/20 0.31
NHERF1 O14745 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6325163 0.86 CBFB (0.52) HSD17B10CBFBMAOADYRK1ATDP1
SCHEMBL4976888 0.82 KDM4E (0.31)
SCHEMBL9305475 0.82 KIF11 (0.39) HSD17B10TYMS
SCHEMBL11808209 0.81 KIF11 (0.38) HSD17B10TYMSRIPK1
SCHEMBL10707110 0.79 CNR1 (0.37)
SCHEMBL7977592 0.79 KDM4E (0.38) HSD17B10PARP1
SCHEMBL727387 0.79 TYMS (0.49) HSD17B10CBFBTYMSTDP1ILK
SCHEMBL19364508 0.79 HSD17B10 (0.40) HSD17B10CBFBMAOADYRK1ATYMS
SCHEMBL889001 0.79 HSD17B10 (0.47) HSD17B10CBFBMAOADYRK1ATDP1
SCHEMBL21708439 0.78 MAOA (0.40) CBFBMAOADYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240230952-A1 LAMINATE AND METHOD FOR MANUFACTURING LAMINATE FUJIFILM CORPORATION (JP) 2024-07-11 US disclosed
US-20240027897-A1 LAMINATE AND MANUFACTURING METHOD OF LAMINATE FUJIFILM CORPORATION (JP) 2024-01-25 US disclosed
US-20230384671-A1 LAMINATE OF NEGATIVE TONE LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF PREPARING NEGATIVE TONE LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2023-11-30 US disclosed
US-9274422-B2 Photosensitive resin composition, method for forming pattern-cured film using photosensitive resin composition, and electronic component HITACHI CHEMICAL DUPONT MICROSYSTEMS, LTD. (JP) 2016-03-01 US disclosed
US-20140120462-A1 PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR FORMING PATTERN-CURED FILM USING PHOTOSENSITIVE RESIN COMPOSITION, AND ELECTRONIC COMPONENT HITACHI CHEMICAL DUPONT MICROSYSTEMS, LTD. (JP) 2014-05-01 US disclosed
CN-1642941-A 1-N-aminobenzimidazole derivatives ZERIA PHARM CO LTD (JP) 2005-07-20 CN disclosed
US-20050148634-A1 1-N-Aminobenzimidazole derivatives ZERIA PHARMACEUTICAL CO., LTD (JP) 2005-07-07 US disclosed
US-6906078-B2 Method of using (H+/K+) ATPase inhibitors as antiviral agents PHARMACIA CORPORATION (US) 2005-06-14 US disclosed
US-6855710-B2 Substituted indolines with an inhibitory effect on various kinases and complexes of CDKs BOEHRINGER INGELHEIM PHARMA KG (DE) 2005-02-15 US disclosed
US-6838465-B2 N-acyltetrahydroisoquinoline derivatives BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-01-04 US disclosed
EP-1167369-A1 NOVEL THIAZOLOBENZIMIDAZOLE DERIVATIVES YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 2002-01-02 EP disclosed
US-20010047038-A1 Method of using (H+/K+) ATPase inhibitors as antiviral agents MOORMAN ALAN E (US) 2001-11-29 US disclosed
WO-2001034573-A1 COMPOUNDS ASTRAZENECA AB (SE) 2001-05-17 WO disclosed
CN-1271731-A New thiazole benzimidazole derivative YAMANOUCHI PHARMA CO LTD (JP) 2000-11-01 CN disclosed
US-5945425-A ADENOSINE TRIPHOSPHASE INHIBITOR; DNA VIRICIDE G.D. SEARLE & CO. (US) 1999-08-31 US disclosed
EP-0457331-B1 Piperidine derivatives and antiulcer composition containing the same MEIJI SEIKA KAISHA (JP) 1996-11-20 EP disclosed
WO-1995029897-A1 METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS G.D. SEARLE & CO. (US) 1995-11-09 WO disclosed
US-5185347-A PIPERIDINE COMPOUNDS AND ANTIULCER COMPOSITION CONTAINING THE SAME MEIJI SEIKA KAISHA LTD. (JP) 1993-02-09 US disclosed
EP-0457331-A1 Piperidine derivatives and antiulcer composition containing the same MEIJI SEIKA KAISHA LTD. (JP) 1991-11-21 EP disclosed
US-4772619-A ANTIULCER AGENTS G. D. SEARLE & CO. (US) 1988-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050148634-A1 1-N-Aminobenzimidazole derivatives CYP1B1, CYP2E1, CYP1A1 HSD17B10 247/4885CBFB 755/4885MAOA 272/4885
US-20010047038-A1 Method of using (H+/K+) ATPase inhibitors as antiviral agents ATP4A, ATP1A1, ATP1A4 HSD17B10 954/4885CBFB 2862/4885MAOA 1944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.