SCHEMBL6324425

SCHEMBL6324425

NC(=O)c1cccc(NC(=O)NS(=O)(=O)c2ccccc2)c1

nearest known ligand 0.56

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
CA12 O43570 3/20 0.54
CA9 Q16790 3/20 0.54
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
MAPT P10636 1/20 0.54
CYP2C9 P11712 1/20 0.52
PARP1 P09874 6/20 0.51
PARP10 Q53GL7 5/20 0.51
PARP15 Q460N3 4/20 0.51
PARP14 Q460N5 2/20 0.51
ATIC P31939 1/20 0.51
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 1/20 0.50
FBP1 P09467 1/20 0.49
CAMK2D Q13557 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6326204 0.88 LMNA (0.67) LMNACA12CA9CA1CA2
SCHEMBL6326162 0.88 FLT1 (0.54) LMNACA12CA9CA1CA2
SCHEMBL6323770 0.87 CSF1R (0.56) LMNAPARP1MEN1KMT2AFBP1
SCHEMBL6326710 0.84 RAB9A (0.62) LMNAMAPTCYP2C9MEN1KMT2A
SCHEMBL10386046 0.82 ATIC (0.71) CA1CA2MAPTATICMEN1
SCHEMBL30493181 0.82 ATIC (0.71) CA1CA2MAPTATICMEN1
SCHEMBL3462271 0.82 MEN1 (0.72) LMNACA12CA9CA1CA2
SCHEMBL4196236 0.82 LMNA (0.78) LMNACA12CA9CA1CA2
SCHEMBL8779145 0.82 POLB (0.59) LMNACA1CA2CYP2C9MEN1
SCHEMBL6329891 0.82 CA12 (0.55) LMNACA12CA9CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858565-B2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2005-02-22 US disclosed
US-20030040434-A1 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2003-02-27 US disclosed
EP-1264707-A2 Thermosensitive recording material and novel color developer compounds OJI PAPER CO., LTD. (JP) 2002-12-11 EP disclosed