Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29191002 | 0.85 | POLB (0.51) | MAPK1BCHECES1MAPTMEN1 | |
| SCHEMBL6325959 | 0.81 | AR (0.51) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL28954485 | 0.77 | BCHE (0.48) | MAPK1BCHECES1SMN1; SMN2CES2 | |
| SCHEMBL27765 | 0.73 | MAPK1 (1.00) | MAPK1CES1MAPTMEN1NPC1 | |
| SCHEMBL6324751 | 0.73 | SRD5A2 (0.51) | MAPK1CES1MAPTLMNACES2 | |
| SCHEMBL6325746 | 0.73 | CES1 (0.57) | MAPK1BCHECES1SMN1; SMN2CES2 | |
| SCHEMBL29114323 | 0.72 | NOS1 (0.63) | MAPK1BCHECES1MAPTMEN1 | |
| Methyl Alcohol SCHEMBL28098714 | 0.71 | MAPK1 (0.96) | MAPK1CES1MAPTMEN1NPC1 | |
| Ammonia Solution, Strong SCHEMBL17180526 | 0.71 | MAPK1 (0.96) | MAPK1CES1MAPTMEN1NPC1 | |
| Bromide SCHEMBL8031021 | 0.71 | MAPK1 (0.96) | MAPK1CES1MAPTMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050124664-A1 | Urea thiadiazole inhibitors of plasminogen activator inhibior-1 | BRISTOL-MYERS SQUIBB CO. | 2005-06-09 | — | — | US | disclosed |
| US-20050080089-A1 | Formulations comprising triazoles and alkoxylated amines | AKZO NOBEL CHEMICALS BV (NL) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080089-A1 | Formulations comprising triazoles and alkoxylated amines | ALKBH3, TYR, NAT1 | MAPK1 1964/4885BCHE 142/4885CES1 1071/4885 |
| US-20050124664-A1 | Urea thiadiazole inhibitors of plasminogen activator inhibior-1 | SERPINE1, SERPINC1, SERPINB1 | MAPK1 907/4885BCHE 2998/4885CES1 379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.