Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | RECQL | P46063 | 7/20 | 0.62 |
| ▸ | BLM | P54132 | 5/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.62 |
| ▸ | APEX1 | P27695 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.62 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | DRD2 | P14416 | 2/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14100469 | 1.00 | TDP1 (0.62) | TDP1KDM4EMAPTRECQLBLM | |
| SCHEMBL14100446 | 1.00 | TDP1 (0.62) | TDP1KDM4EMAPTRECQLBLM | |
| SCHEMBL11810875 | 0.88 | TRPA1 (0.61) | TDP1KDM4EMAPTRECQLBLM | |
| Bromide SCHEMBL9513709 | 0.81 | SHBG (0.51) | TDP1KDM4EMAPTRECQLBLM | |
| SCHEMBL683547 | 0.81 | HSD17B10 (0.69) | TDP1KDM4EMAPTRECQLBLM | |
| SCHEMBL11880606 | 0.80 | TDP1 (0.58) | TDP1KDM4EMAPTRECQLBLM | |
| SCHEMBL16564149 | 0.80 | NFKB1 (0.71) | BLMLMNAHPGDMAPK1CYP3A4 | |
| SCHEMBL18473537 | 0.79 | TDP1 (0.50) | TDP1KDM4EMAPTRECQLBLM | |
| SCHEMBL26061215 | 0.79 | TDP1 (0.50) | TDP1KDM4EMAPTRECQLBLM | |
| SCHEMBL4993623 | 0.78 | TDP1 (0.54) | TDP1KDM4EMAPTRECQLBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9171710-B2 | Mass spectrometric analysis using nanoparticle matrices | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2015-10-27 | — | — | US | claimed |
| US-20150076340-A1 | MASS SPECTROMETRIC ANALYSIS USING NANOPARTICLE MATRICES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA | 2015-03-19 | — | — | US | claimed |
| WO-2014100630-A1 | SYNTHESIS AND SURFACE FUNCTIONALIZATION OF PARTICLES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2014-06-26 | — | — | WO | claimed |
| CN-117903072-A | Dopa compound and preparation method and application thereof | 深圳市松柏科工股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| US-9171710-B2 | Mass spectrometric analysis using nanoparticle matrices | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2015-10-27 | — | — | US | disclosed |
| US-20150076340-A1 | MASS SPECTROMETRIC ANALYSIS USING NANOPARTICLE MATRICES | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA | 2015-03-19 | — | — | US | disclosed |
| US-20140179941-A1 | Synthesis and Surface Functionalization of Particles | BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2014-06-26 | — | — | US | disclosed |
| EP-1866357-B1 | (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF | SHOWA DENKO KK (JP) | 2012-02-22 | — | — | EP | disclosed |
| US-20120022086-A1 | CATECHOLAMINE DERIVATIVES FOR OBESITY AND NEUROLOGICAL DISORDERS | EMORY UNIVERSITY (US) | 2012-01-26 | — | — | US | disclosed |
| US-8044235-B2 | (Meth) acryloyl group-containing aromatic isocyanate compound and production process thereof | SHOWA DENKO K.K. (JP) | 2011-10-25 | — | — | US | disclosed |
| US-20090054543-A1 | (Meth) Acryloyl Group-Containing Aromatic Isocyanate Compound and Production Process Thereof | SHOWA DENKO K.K. (JP) | 2009-02-26 | — | — | US | disclosed |
| EP-1866357-A1 | (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF | Showa Denko K.K. (JP) | 2007-12-19 | — | — | EP | disclosed |
| WO-2006103979-A1 | (METH)ACRYLOYL GROUP-CONTAINING AROMATIC ISOCYANATE COMPOUND AND PRODUCTION PROCESS THEREOF | SHOWA DENKO K.K. (JP) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022086-A1 | CATECHOLAMINE DERIVATIVES FOR OBESITY AND NEUROLOGICAL DISORDERS | BDNF, NTRK2, COMT | TDP1 331/4885KDM4E 2077/4885MAPT 415/4885 |
| US-20090054543-A1 | (Meth) Acryloyl Group-Containing Aromatic Isocyanate Compound and Production Process Thereof | PRMT5, ACR, PRMT1 | TDP1 3531/4885KDM4E 620/4885MAPT 1321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.