Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 10/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6327914 | 0.86 | MAPT (0.56) | PARP1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL6334598 | 0.84 | LMNA (0.62) | PARP1ALDH1A1MAPTTSHRHTT | |
| SCHEMBL6324019 | 0.83 | MAPT (0.59) | PARP1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL6328130 | 0.82 | TSHR (0.68) | PARP1ALDH1A1MAPTTSHRHTT | |
| SCHEMBL6326044 | 0.80 | MAPT (0.56) | PARP1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL6324067 | 0.78 | MAPT (0.72) | PARP1ALDH1A1MAPTTSHRHTT | |
| SCHEMBL6331273 | 0.75 | MAPT (0.48) | PARP1KMT2AALDH1A1MAPTTSHR | |
| SCHEMBL6328650 | 0.72 | PARP1 (0.57) | PARP1KMT2A | |
| SCHEMBL6326450 | 0.72 | ALDH1A1 (0.54) | KMT2AALDH1A1MAPTTSHRPOLB | |
| SCHEMBL6333326 | 0.70 | NPSR1 (0.50) | KMT2AALDH1A1MAPTTSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6924284-B2 | PARP inhibitors | ICOS CORPORATION (US) | 2005-08-02 | — | — | US | disclosed |