Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.31 |
| ▸ | CDK9 | P50750 | 2/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6330870 | 0.90 | GYS1 (0.36) | JAK1PDK4USP30CCNT1CDK9 | |
| SCHEMBL6334303 | 0.84 | TSHR (0.32) | JAK1LMNATSHRPDK4USP30 | |
| SCHEMBL6340611 | 0.83 | LMNA (0.33) | JAK1LMNATSHRPDK4USP30 | |
| SCHEMBL6333427 | 0.81 | HTR2C (0.39) | PDK4WDR5 | |
| SCHEMBL6339270 | 0.73 | GYS1 (0.37) | JAK1PDK4CCNT1CDK9NR1H2 | |
| SCHEMBL1770789 | 0.73 | LMNA (0.34) | LMNAUSP30NR1H2NR1H3WDR5 | |
| SCHEMBL6492320 | 0.73 | HTR1D (0.37) | JAK1PDK4CCNT1CDK9CNR1 | |
| SCHEMBL6492149 | 0.72 | TDO2 (0.46) | HTR1D | |
| SCHEMBL6504144 | 0.71 | HTR2A (0.36) | JAK1PDK4NR1H2NR1H3WDR5 | |
| Hydrochloric Acid SCHEMBL6334531 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881733-B1 | Serotonergic benzofurans | ELI LILLY AND COMPANY (US) | 2005-04-19 | — | — | US | disclosed |
| EP-1204659-B1 | SEROTONERGIC BENZOFURANS | LILLY CO ELI (US) | 2003-11-26 | — | — | EP | disclosed |