Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6339270 | 0.90 | GYS1 (0.37) | NR1H2NR1H3JAK1PDK4GPR119 | |
| SCHEMBL6335122 | 0.84 | TSHR (0.34) | LMNATSHRUSP30GRM5PDK4 | |
| SCHEMBL6334848 | 0.83 | GYS1 (0.34) | USP30NR1H2NR1H3GRM5GPR119 | |
| SCHEMBL6332995 | 0.83 | JAK1 (0.32) | LMNATSHRUSP30NR1H2NR1H3 | |
| SCHEMBL6330650 | 0.78 | NR1H2 (0.33) | USP30NR1H2NR1H3GRM5GPR119 | |
| Hydrochloric Acid SCHEMBL7474626 | 0.78 | CDK9 (0.32) | JAK1CCNT1CDK9 | |
| SCHEMBL6502167 | 0.73 | TDO2 (0.45) | DRD2HTR1DHTR1BHTR2A | |
| SCHEMBL6330870 | 0.73 | GYS1 (0.36) | USP30NR1H2NR1H3JAK1GRM5 | |
| Hydrochloric Acid SCHEMBL6338676 | 0.70 | CCNT1 (0.36) | HTR2CCCNT1CDK9 | |
| SCHEMBL429243 | 0.68 | SSTR4 (0.38) | GRM5PDK4GPR119MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881733-B1 | Serotonergic benzofurans | ELI LILLY AND COMPANY (US) | 2005-04-19 | — | — | US | disclosed |
| EP-1204659-B1 | SEROTONERGIC BENZOFURANS | LILLY CO ELI (US) | 2003-11-26 | — | — | EP | disclosed |