Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 known ✓ | P30556 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.57 |
| ▸ | MLNR | O43193 | 1/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8746883 | 0.91 | LTA4H (0.64) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| Sulfuric Acid SCHEMBL27884252 | 0.87 | LTA4H (0.64) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| Sulfuric Acid SCHEMBL27884236 | 0.87 | LTA4H (0.64) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| Sulfuric Acid SCHEMBL28310397 | 0.87 | LTA4H (0.64) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| Sulfuric Acid SCHEMBL27901380 | 0.87 | LTA4H (0.64) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| Sulfuric Acid SCHEMBL30568760 | 0.87 | LTA4H (0.64) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| Sulfuric Acid SCHEMBL1774943 | 0.87 | LTA4H (0.64) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| Sulfuric Acid SCHEMBL6663317 | 0.87 | LTA4H (0.64) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| Sulfuric Acid SCHEMBL999423 | 0.87 | LTA4H (0.64) | LTA4HMLNRNR1I2ESR1NR3C1 | |
| Sulfuric Acid SCHEMBL27901381 | 0.87 | LTA4H (0.64) | LTA4HMLNRNR1I2ESR1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6849676-B1 | Antistatic polyurethane elastic fiber and material for producing the same | MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) | 2005-02-01 | — | — | US | disclosed |