SCHEMBL634002

SCHEMBL634002

CCC(=O)c1cccc(C)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.59
TDP1 Q9NUW8 1/20 0.59
PARP1 P09874 1/20 0.59
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
CTNNB1 P35222 3/20 0.54
WNT3A P56704 3/20 0.54
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.52
TAS1R3 Q7RTX0 1/20 0.51
TAS1R1 Q7RTX1 1/20 0.51
MAPT P10636 2/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
HTT P42858 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
KCNK3 O14649 1/20 0.50
KCNH2 Q12809 1/20 0.50
KCNK9 Q9NPC2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10389972 0.87 SMN1; SMN2 (0.54) HPGDTDP1MEN1KMT2ASMN1; SMN2
SCHEMBL29062364 0.85 CTNNB1 (0.70) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL30089541 0.85 CTNNB1 (0.70) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL28728190 0.85 MEN1 (0.64) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL29456641 0.85 MEN1 (0.64) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL14982191 0.85 HDAC8 (0.53) HPGDTDP1PARP1HDAC8HDAC6
Propiophenone SCHEMBL16178576 0.84 SMN1; SMN2 (0.50) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL2027904 0.84 CTNNB1 (0.59) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL29639747 0.83 HPGD (0.59) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL910158 0.83 HPGD (0.59) HPGDTDP1PARP1HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 612 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325204-A Low-temperature-rise rubber and carbon black composition and preparation method thereof 华南理工大学 2024-07-12 CN claimed
CN-117568821-A Electrochemical synthesis method of quinoxaline derivative 齐齐哈尔医学院 2024-02-20 CN claimed
CN-117250289-A Method for detecting content of p-methyl propiophenone in sample 湖南新领航检测技术有限公司 2023-12-19 CN claimed
WO-2023115621-A1 METHOD FOR PREPARING Α-HALOGENATED ACETOPHENONE COMPOUND UNDER CATALYSIS OF IONIC LIQUID [TEA][TFOH]2 大连大学 2023-06-29 WO claimed
CN-116297919-A 2, 5-dimethyl acetophenone gas chromatography detection method 重庆康普化学工业股份有限公司 2023-06-23 CN claimed
CN-115028519-A Novel synthesis method of dexmedetomidine intermediate 2, 3-dimethylacetophenone 南京亿华药业有限公司 2022-09-09 CN claimed
CN-114181088-A Ionic liquid (TEA)][TfOH]2Method for preparing alpha-halogenated acetophenone compounds by catalysis 大连大学 2022-03-15 CN claimed
CN-111393272-A Synthetic method of 3' -methyl propiophenone 惠泽化学科技(濮阳)有限公司 2020-07-10 CN claimed
US-20180312531-A1 SILICON-CONTAINING ORGANIC COMPOUND AND APPLICATIONS THEREOF GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2018-11-01 US claimed
CN-106083724-A A kind of preparation method of dexmedetomidine 江苏恒瑞医药股份有限公司 2016-11-09 CN claimed
CN-105017012-A Acetoxylation method of benzyl groups UNIV JIANGXI NORMAL 2015-11-04 CN claimed
EP-4729524-A1 ORGANIC COMPOUND, MIXTURE, COMPOSITION, ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY PANEL Shenzhen China Star Optoelectronics Semiconductor Display Technology Co., Ltd. (CN) 2026-04-22 EP disclosed
US-20260060001-A1 ORGANIC COMPOUND, MIXTURE, COMPOSITION, ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY PANEL GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2026-02-26 US disclosed
US-20260027148-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS BEXSON BIOMEDICAL INC (US) 2026-01-29 US disclosed
US-20260014191-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS BEXSON BIOMEDICAL INC (US) 2026-01-15 US disclosed
EP-0114607-B1 DIBENZOYL METHANE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND THEIR USE HAARMANN & REIMER GMBH (DE) 1985-09-04 EP disclosed
US-4489057-A DIBENZOYLMETHANE COMPOUNDS MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1984-12-18 US disclosed
EP-0114607-A1 Dibenzoyl methane derivatives, process for their production and their use HAARMANN & REIMER GMBH (DE) 1984-08-01 EP disclosed
US-4017313-A Photosensitive composition containing a leuco dye, a photosensitizer, an aromatic aldehyde and a secondary or tertiary amine and the use thereof in a direct-print process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-12 US disclosed
US-3931152-A ANTITUBERCULAR AMERICAN CYANAMID COMPANY (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180312531-A1 SILICON-CONTAINING ORGANIC COMPOUND AND APPLICATIONS THEREOF TEAD2, TEAD1, TEAD3 HPGD 4527/4885TDP1 972/4885PARP1 2509/4885
US-20260014191-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS SLC6A4, SLC6A3, SIGMAR1 HPGD 3922/4885TDP1 2410/4885PARP1 4499/4885
US-20260027148-A1 COMPLEXING AGENT SALT FORMULATIONS OF PHARMACEUTICAL COMPOUNDS SLC6A3, SIGMAR1, SLC6A4 HPGD 4135/4885TDP1 1734/4885PARP1 4388/4885
US-20260060001-A1 ORGANIC COMPOUND, MIXTURE, COMPOSITION, ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY PANEL LAS1L, SRD5A1, LSM8 HPGD 4591/4885TDP1 3944/4885PARP1 1779/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.