SCHEMBL910158

SCHEMBL910158

Cc1cccc(C(=O)CO)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.59
TDP1 Q9NUW8 1/20 0.59
PARP1 P09874 1/20 0.59
HDAC8 Q9BY41 1/20 0.55
HDAC6 Q9UBN7 1/20 0.55
CTNNB1 P35222 4/20 0.54
WNT3A P56704 4/20 0.54
SMN1; SMN2 Q16637 2/20 0.52
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
KDM4E B2RXH2 1/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
HTT P42858 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
KCNK3 O14649 1/20 0.50
KCNH2 Q12809 1/20 0.50
KCNK9 Q9NPC2 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29639747 1.00 HPGD (0.59) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL9037216 0.88 HPGD (0.53) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL28728190 0.85 MEN1 (0.64) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL29062364 0.85 CTNNB1 (0.70) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL30089541 0.85 CTNNB1 (0.70) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL29456641 0.85 MEN1 (0.64) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL12235278 0.84 TDP1 (0.48) HPGDTDP1SMN1; SMN2MEN1KMT2A
SCHEMBL634002 0.83 HPGD (0.59) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL6934563 0.82 PARP1 (0.62) HPGDTDP1PARP1HDAC8HDAC6
SCHEMBL5883556 0.82 TRPA1 (0.57) HPGDTDP1PARP1HDAC8HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117534643-B Donor-acceptor supermolecule fluorescent probe and application thereof in pyrethroid pesticide residue detection 中国科学院合肥物质科学研究院 2025-04-18 CN claimed
CN-114324664-B Method for detecting volatile components in lotus paste stuffing 广州酒家集团利口福食品有限公司 2024-05-03 CN claimed
CN-117534643-A Donor-acceptor supermolecule fluorescent probe and application thereof in pyrethroid pesticide residue detection 中国科学院合肥物质科学研究院 2024-02-09 CN claimed
CN-116770308-B Film stripping liquid suitable for ultra-fine circuit manufacturing and application thereof 昆山市板明电子科技有限公司 2023-11-14 CN claimed
CN-114751870-B 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxybenzoate and derivative thereof, and synthetic method and application thereof 贵州医科大学 2023-10-20 CN claimed
CN-116770308-A Film stripping liquid suitable for ultra-fine circuit manufacturing and application thereof 昆山市板明电子科技有限公司 2023-09-19 CN claimed
CN-115420830-B GC-MS method for quantitatively detecting volatile components of golden bell oral liquid 山东宏济堂制药集团股份有限公司 2023-06-23 CN claimed
CN-111272906-B Method for determining flower fragrance components in main stream smoke of cigarette 中国烟草总公司郑州烟草研究院 2022-12-20 CN claimed
CN-115420830-A GC-MS method for quantitatively detecting volatile components of golden scallop oral liquid 山东宏济堂制药集团股份有限公司 2022-12-02 CN claimed
CN-114751870-A 2- (isoxazole-5-yl) phenyl-3, 4-dihydroxy benzoate and derivative thereof, and synthesis method and application thereof 贵州医科大学 2022-07-15 CN claimed
CN-111272906-A Method for determining flower fragrance components in main stream smoke of cigarette 中国烟草总公司郑州烟草研究院 2020-06-12 CN claimed
CN-111269383-A Self-repairing polyurethane elastomer without external stimulation and preparation method thereof 青岛科技大学 2020-06-12 CN claimed
CN-105669747-A Preparing method of alpha-hydroxy phosphate 苏州大学张家港工业技术研究院 2016-06-15 CN claimed
US-8592621-B2 Precursor compounds of sweet taste receptor antagonists for the prevention or treatment of disease SYMRISE AG (DE) 2013-11-26 US claimed
US-20110045069-A1 PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE SYMRISE GMBH CO. KG (DE) 2011-02-24 US claimed
EP-0031253-B1 PROCESS FOR PREPARING 3,4-SUBSTITUTED BENZALDEHYDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-10-05 EP claimed
US-4335263-A MANY STEPS, STARTING WITH ACETYLATION OF M-CRESOL OR P-CRESOL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-06-15 US claimed
EP-0031253-A1 Process for preparing 3,4-substituted benzaldehydes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-07-01 EP claimed
US-3981311-A Aromatic compositions FIRMENICH S.A. (CH) 1976-09-21 US claimed
US-3947603-A PHENOLS FIRMENICH & CIE (CH) 1976-03-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110045069-A1 PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE TAS1R2, TAS2R5, TAS2R1 HPGD 974/4885TDP1 4364/4885PARP1 4108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.