Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | G6PD | P11413 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10589344 | 0.87 | HTR6 (0.55) | ALOX15G6PDCASP7CASP6GAA | |
| Ether SCHEMBL2357461 | 0.87 | MAPT (0.40) | ALOX15G6PDCASP7CASP6GAA | |
| SCHEMBL17331336 | 0.85 | MEN1 (0.46) | ALOX15G6PDCASP7CASP6MEN1 | |
| SCHEMBL13908249 | 0.84 | MMP2 (0.53) | GAAL3MBTL1MEN1KMT2APOLB | |
| SCHEMBL7707773 | 0.84 | G6PD (0.57) | ALOX15G6PDCASP7CASP6GAA | |
| SCHEMBL19040679 | 0.83 | AKR1C3 (0.46) | ALOX15GAAL3MBTL1MEN1KMT2A | |
| SCHEMBL9618781 | 0.80 | MYC (0.50) | ALOX15G6PDCASP7CASP6MEN1 | |
| SCHEMBL29204880 | 0.80 | GAA (0.48) | GAAL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL2068967 | 0.79 | KMT2A (0.53) | GAAL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL11441295 | 0.77 | POLB (0.45) | GAAL3MBTL1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058977-A1 | Sulfonyl-containing 2,3-diarylindole compounds, methods for making same, and methods of use thereof | INSTITUTE OF MATERIA MEDIC, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2004-03-25 | — | — | US | claimed |
| US-9701627-B2 | LRRK2 GTP binding inhibitors for treatment of Parkinson's disease and neuroinflammatory disorders | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2017-07-11 | — | — | US | disclosed |
| US-20150361038-A1 | LRRK2 GTP BINDING INHIBITORS FOR TREATMENT OF PARKINSON'S DISEASE AND NEUROINFLAMMATORY DISORDERS | UNIVERSITY OF MARYLAND, BALTIMORE | 2015-12-17 | — | — | US | disclosed |
| US-6960611-B2 | Sulfonyl-containing 2,3-diarylindole compounds, methods for making same, and methods of use thereof | INSTITUTE OF MATERIA MEDICA (CN) | 2005-11-01 | — | — | US | disclosed |
| US-20040058977-A1 | Sulfonyl-containing 2,3-diarylindole compounds, methods for making same, and methods of use thereof | INSTITUTE OF MATERIA MEDIC, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2004-03-25 | — | — | US | disclosed |
| EP-1099687-B1 | PROCESS FOR PRODUCING 2-AMINOBENZOPHENONE COMPOUND | NISSAN CHEMICAL IND LTD (JP) | 2004-02-11 | — | — | EP | disclosed |
| US-6310249-B1 | HEATING AN ARYLSULFONAMIDE COMPOUND IN THE PRESENCE OF ALUMINUM CHLORIDE TO FORM 2-AMINOBENZOPHENONE COMPOUND | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-1099687-A1 | PROCESS FOR PRODUCING 2-AMINOBENZOPHENONE COMPOUND | Nissan Chemical Industries, Ltd. (JP) | 2001-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150361038-A1 | LRRK2 GTP BINDING INHIBITORS FOR TREATMENT OF PARKINSON'S DISEASE AND NEUROINFLAMMATORY DISORDERS | LRRK2, PARK7, SNCA | ALOX15 2875/4885G6PD 4283/4885CASP7 3630/4885 |
| US-20040058977-A1 | Sulfonyl-containing 2,3-diarylindole compounds, methods for making same, and methods of use thereof | PTGS2, PTGES2, PTGER2 | ALOX15 55/4885G6PD 309/4885CASP7 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.