Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6573094 | 0.81 | GAA (0.42) | FFAR1SYKGAAHPGDKDM4E | |
| SCHEMBL31391958 | 0.79 | HRH3 (0.41) | FFAR1SYKGAAHPGDKDM4E | |
| SCHEMBL634910 | 0.79 | LTA4H (0.45) | FFAR1SYKGAAHPGDKDM4E | |
| SCHEMBL19948940 | 0.79 | FFAR1 (0.38) | FFAR1SYKGAAHPGDKDM4E | |
| SCHEMBL3452132 | 0.79 | CA12 (0.50) | HSD17B10MAOBCYP19A1 | |
| SCHEMBL4476065 | 0.79 | CYP2A6 (0.54) | FFAR1GAAHPGDKDM4EALDH1A1 | |
| SCHEMBL11403419 | 0.79 | LTA4H (0.47) | ALDH1A1MAOBP2RX3APPCYP19A1 | |
| SCHEMBL187687 | 0.78 | ALDH3A1 (0.50) | SYKKDM4EALDH1A1L3MBTL1MAOB | |
| SCHEMBL6572089 | 0.78 | MEN1 (0.45) | FFAR1SYKGAAHPGDKDM4E | |
| SCHEMBL4849887 | 0.77 | FFAR1 (0.44) | FFAR1GAAHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120253038-A1 | PROCESSES FOR THE SYNTHESIS OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF | SANDOZ AG (CH) | 2012-10-04 | — | — | US | claimed |
| CN-102395561-A | Processes for the synthesis of bazedoxifene acetate and intermediates thereof | SANDOZ AG | 2012-03-28 | — | — | CN | claimed |
| EP-2419406-A1 | PROCESSES FOR THE SYNTHESIS OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF | Sandoz AG (CH) | 2012-02-22 | — | — | EP | claimed |
| WO-2010118997-A1 | PROCESSES FOR THE SYNTHESIS OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF | SANDOZ AG (CH) | 2010-10-21 | — | — | WO | claimed |
| JP-62198654-A | — | — | None | — | — | JP | disclosed |
| US-11332459-B2 | Benzimidazole derivatives and their uses | TEIJIN PHARMA LIMITED (JP) | 2022-05-17 | — | — | US | disclosed |
| US-20200308145-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USES | AMGEN INC. (US) | 2020-10-01 | — | — | US | disclosed |
| WO-2018202681-A1 | USE OF DISUBSTITUTED BENZENES TO CONTROL INSECTICIDE-RESISTANT PESTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-11-08 | — | — | WO | disclosed |
| US-8889896-B2 | Process for the preparation of bazedoxifene acetate and intermediates thereof | Divi's Laboratories, Ltd. (IN) | 2014-11-18 | — | — | US | disclosed |
| US-8889896-B2 | Process for the preparation of bazedoxifene acetate and intermediates thereof | Divi's Laboratories, Ltd. (IN) | 2014-11-18 | — | — | US | disclosed |
| US-8889896-B2 | Process for the preparation of bazedoxifene acetate and intermediates thereof | Divi's Laboratories, Ltd. (IN) | 2014-11-18 | — | — | US | disclosed |
| US-20130289296-A1 | NOVEL PROCESS FOR THE PREPARATION OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF | DIVI'S LABORATORIES LTD. (IN) | 2013-10-31 | — | — | US | disclosed |
| WO-2010118997-A1 | PROCESSES FOR THE SYNTHESIS OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF | SANDOZ AG (CH) | 2010-10-21 | — | — | WO | disclosed |
| US-7247756-B2 | 1,4-disubstituted benzenes as insecticides | BAYER CROPSCIENCE AG (DE) | 2007-07-24 | — | — | US | disclosed |
| US-6753429-B2 | FOR USE AS INSECTICIDES AGAINST A VARIETY OF INSECTS, INCLUDING LARVAE, SUCH AS TOBACCO BUDWORM | FMC CORPORATION | 2004-06-22 | — | — | US | disclosed |
| US-20030207894-A1 | 1,4-Disubstituted benzenes as insecticides | BAYER CROPSCIENCE AG (DE) | 2003-11-06 | — | — | US | disclosed |
| EP-1334083-A2 | 1,4-DISUBSTITUTED BENZENES AS INSECTICIDES | FMC CORPORATION (US) | 2003-08-13 | — | — | EP | disclosed |
| US-20020183342-A1 | 1,4-Disubstituted benzenes as insecticides | BAYER CROPSCIENCE AG (DE) | 2002-12-05 | — | — | US | disclosed |
| WO-2002017712-A2 | DISUBSTITUTED BENZENES AS INSECTICIDES | FMC CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |
| JP-S62198654-A | (HALOMETHYLPHENOXY)-ACETONITRILE AND PRODUCTION THEREOF | HODOGAYA CHEM CO LTD | 1987-09-02 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207894-A1 | 1,4-Disubstituted benzenes as insecticides | DDT, CYP1B1, CYP4B1 | FFAR1 971/4885SYK 3190/4885GAA 4175/4885 |
| US-20200308145-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USES | TRPC6, TRPV6, TRPM6 | FFAR1 1117/4885SYK 1825/4885GAA 2631/4885 |
| US-20120253038-A1 | PROCESSES FOR THE SYNTHESIS OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF | CYP19A1, HSD17B11, CYP2F1 | FFAR1 108/4885SYK 4796/4885GAA 1506/4885 |
| US-20130289296-A1 | NOVEL PROCESS FOR THE PREPARATION OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF | CYP19A1, HSD17B11, SULT1E1 | FFAR1 65/4885SYK 4843/4885GAA 2339/4885 |
| US-11332459-B2 | Benzimidazole derivatives and their uses | TRPC6, TRPV6, TRPM6 | FFAR1 1117/4885SYK 1825/4885GAA 2631/4885 |
| US-20020183342-A1 | 1,4-Disubstituted benzenes as insecticides | DDT, CYP1B1, CYP4B1 | FFAR1 971/4885SYK 3190/4885GAA 4175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.