SCHEMBL6348142

SCHEMBL6348142

Cc1ccc(COc2cc[c]cc2)c(C)c1C

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.34
FFAR1 O14842 1/20 0.32
ESR1 P03372 1/20 0.31
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
MAPK1 P28482 1/20 0.31
ESR2 Q92731 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CD274 Q9NZQ7 1/20 0.30
ACHE P22303 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11419601 0.84 MAOB (0.43) MAOBFFAR1ESR1ESR2CD274
SCHEMBL3969062 0.77 TAAR1 (0.42) MAOBTDP1L3MBTL1
SCHEMBL920482 0.76 MAOB (0.57) MAOBFFAR1ACHEKMT2A
SCHEMBL17514961 0.75 MAOB (0.41) MAOBFFAR1
SCHEMBL17514953 0.75 MMP1 (0.51) MAOBFFAR1
SCHEMBL8734299 0.73 PARP10 (0.38) MAOBMAPK1
SCHEMBL5540184 0.71 APP (0.41) MAOBESR1TP53POLBAPEX1
SCHEMBL11491629 0.70 SMN1; SMN2 (0.41) KMT2A
SCHEMBL5537450 0.69 LMNA (0.40) MAOBFFAR1MAPK1KMT2A
SCHEMBL4053035 0.69 FFAR1 (0.48) MAOBFFAR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050101783-A1 N-(heterocycle-methyl)alkylamine derivative, process for producing the same, and bactericide KUREHA CORPORATION (JP) 2005-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050101783-A1 N-(heterocycle-methyl)alkylamine derivative, process for producing the same, and bactericide HBZ, ACMSD, HDHD5 MAOB 741/4885FFAR1 2675/4885ESR1 4653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.