Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 16/20 | 0.61 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6349003 | 0.90 | SIRT2 (0.49) | SIRT2ALBKDM4E | |
| SCHEMBL6347687 | 0.89 | METAP2 (0.50) | SIRT2ALBKDM4EMAPT | |
| SCHEMBL6358696 | 0.88 | SIRT2 (0.63) | SIRT2ALBF10KDM4EALDH1A1 | |
| SCHEMBL6351360 | 0.80 | METAP2 (0.55) | SIRT2KDM4EMAPT | |
| SCHEMBL6353746 | 0.79 | SIRT2 (0.61) | SIRT2ALBALDH1A1MAPT | |
| SCHEMBL6349554 | 0.78 | AKR1C2 (0.48) | SIRT2KDM4E | |
| SCHEMBL7063908 | 0.78 | METAP2 (0.50) | SIRT2ALBKDM4E | |
| SCHEMBL6833917 | 0.78 | MAPK1 (0.50) | SIRT2KDM4EALDH1A1 | |
| SCHEMBL6357252 | 0.77 | SIRT2 (0.65) | SIRT2ALBALDH1A1MAPT | |
| SCHEMBL15838774 | 0.76 | SIRT2 (1.00) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | SIRT2 3380/4885ALB 1682/4885F10 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.