Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.63 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6349299 | 0.88 | SIRT2 (0.61) | SIRT2ALBKDM4EF10ALDH1A1 | |
| SCHEMBL6351360 | 0.85 | METAP2 (0.55) | SIRT2KDM4EMAPK1HTTLMNA | |
| SCHEMBL6347994 | 0.83 | KCNK2 (0.52) | SIRT2ALBKDM4EMAPK1HTT | |
| SCHEMBL6358978 | 0.81 | ALB (0.55) | ALBHTTF10MEN1KMT2A | |
| SCHEMBL6709145 | 0.80 | SIRT2 (0.56) | SIRT2KDM4EMAPK1HTTALDH1A1 | |
| SCHEMBL6353693 | 0.80 | ALB (0.55) | SIRT2ALBKDM4EHTTF10 | |
| SCHEMBL6359077 | 0.78 | ALB (0.56) | ALBKDM4EHTTF10MEN1 | |
| SCHEMBL6355513 | 0.78 | ALB (0.56) | ALBKDM4EHTTMEN1KMT2A | |
| SCHEMBL6357252 | 0.78 | SIRT2 (0.65) | SIRT2ALBHTTALDH1A1LMNA | |
| SCHEMBL15838774 | 0.77 | SIRT2 (1.00) | SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | SIRT2 3380/4885ALB 1682/4885KDM4E 2637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.