Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921175 | 0.91 | SERPINE1 (0.49) | LMNAKCNMA1 | |
| SCHEMBL6349508 | 0.72 | AKR1C2 (0.49) | LMNAKCNMA1 | |
| SCHEMBL6357624 | 0.71 | CA12 (0.52) | LMNAALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL6349527 | 0.70 | ALDH1A1 (0.61) | LMNAALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL6359043 | 0.69 | CA12 (0.47) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL31549875 | 0.69 | TDP1 (0.70) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL40265 | 0.69 | TDP1 (0.70) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL417476 | 0.68 | SERPINE1 (0.56) | ALDH1A1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL5533137 | 0.68 | MEN1 (0.57) | LMNAALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL16160854 | 0.68 | LMNA (0.59) | LMNAALDH1A1KCNMA1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | LMNA 4552/4885ALDH1A1 462/4885KCNMA1 3819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.