Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 9/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12518271 | 0.88 | ACE (0.50) | ELANECNR2ACEKCNQ1 | |
| SCHEMBL6358938 | 0.87 | ALDH1A1 (0.49) | ELANECTSGACE | |
| SCHEMBL28346449 | 0.85 | CTRB1 (0.54) | ELANECTSG | |
| SCHEMBL8610923 | 0.82 | PREP (0.57) | ELANECTSGACEXIAP | |
| SCHEMBL8961434 | 0.82 | PREP (0.57) | ELANECTSGACEXIAP | |
| SCHEMBL8922930 | 0.82 | PREP (0.57) | ELANECTSGACEXIAP | |
| SCHEMBL7315812 | 0.80 | CTRB1 (0.67) | ELANE | |
| SCHEMBL6359506 | 0.79 | ALDH1A1 (0.51) | ACE | |
| SCHEMBL30440339 | 0.79 | OPRM1 (0.56) | ELANECTSG | |
| SCHEMBL29641544 | 0.79 | OPRM1 (0.56) | ELANECTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222093-A1 | Methods for restoring cognitive function following systemic stress | PEARLMAN RODNEY | 2005-10-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222093-A1 | Methods for restoring cognitive function following systemic stress | CRH, BDNF, CHAT | ELANE 861/4885CNR2 528/4885CTSG 405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.