Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | IL1RN | P18510 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11727554 | 0.83 | AKR1C3 (0.67) | AKR1C3MAPTIL1RNKMT2AMEN1 | |
| SCHEMBL13780083 | 0.81 | PSEN1 (0.65) | AKR1C3KMT2ALMNA | |
| SCHEMBL6810343 | 0.81 | PSEN1 (0.65) | AKR1C3KMT2ALMNA | |
| SCHEMBL12203854 | 0.81 | PSEN1 (0.65) | AKR1C3KMT2ALMNA | |
| SCHEMBL28092047 | 0.81 | AKR1C3 (0.58) | AKR1C3MAPTIL1RNKMT2AMEN1 | |
| SCHEMBL6351883 | 0.81 | AKR1C3 (0.60) | AKR1C3MAPTIL1RNKMT2AMEN1 | |
| SCHEMBL16169927 | 0.80 | PSEN1 (0.52) | AKR1C3KMT2ALMNAALDH1A1 | |
| SCHEMBL22501560 | 0.80 | LMNA (0.74) | AKR1C3MAPTKMT2AMEN1LMNA | |
| SCHEMBL14696960 | 0.78 | ALDH1A1 (0.78) | AKR1C3MAPTIL1RNKMT2AMEN1 | |
| SCHEMBL28004341 | 0.78 | MAPT (0.57) | AKR1C3MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | AKR1C3 3288/4885MAPT 4753/4885IL1RN 2514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.