Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PTGES | O14684 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | RPA1 | P27694 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357975 | 0.91 | MEN1 (0.64) | MEN1KMT2AALDH1A1PTGESALOX5 | |
| SCHEMBL6352363 | 0.88 | MAPT (0.52) | MEN1KMT2AALDH1A1AKR1C2AKR1C1 | |
| SCHEMBL6351288 | 0.87 | PPARG (0.52) | MEN1KMT2AAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL6350870 | 0.85 | PPARG (0.61) | MEN1KMT2AAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL6351026 | 0.83 | LMNA (0.51) | MEN1KMT2AAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL6833361 | 0.83 | PPARG (0.49) | MEN1KMT2AAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL6834099 | 0.81 | PRSS12 (0.42) | MEN1KMT2APTGESALOX5AKR1C2 | |
| SCHEMBL6833903 | 0.80 | MEN1 (0.42) | MEN1KMT2AAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL4103906 | 0.79 | PTGES (0.69) | MEN1KMT2AALDH1A1PTGESALOX5 | |
| SCHEMBL6353643 | 0.78 | LMNA (0.49) | MEN1KMT2AAKR1C2AKR1C1AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | MEN1 3274/4885KMT2A 3645/4885ALDH1A1 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.