Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.61 |
| ▸ | DRD1 | P21728 | 2/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.58 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723832 | 0.89 | DRD2 (0.74) | DRD2DRD1TAAR1OPRK1CALM1 | |
| 3-Phenethylphenol SCHEMBL717571 | 0.86 | OPRK1 (0.74) | DRD2DRD1TAAR1OPRK1CHRM2 | |
| SCHEMBL27854439 | 0.82 | ABCB1 (0.63) | DRD2CALM1GABRA1GABRG2GABRB3 | |
| SCHEMBL23754287 | 0.82 | GABRA1 (0.67) | DRD2DRD1TAAR1OPRK1CALM1 | |
| SCHEMBL8947211 | 0.82 | GABRA1 (0.67) | DRD2DRD1TAAR1OPRK1CALM1 | |
| SCHEMBL29449650 | 0.82 | GABRA1 (0.67) | DRD2DRD1TAAR1OPRK1CALM1 | |
| SCHEMBL5724287 | 0.81 | DRD2 (0.50) | DRD2DRD1TAAR1OPRK1CALM1 | |
| Lunularin SCHEMBL717118 | 0.80 | LTA4H (0.64) | DRD2DRD1TAAR1OPRK1CALM1 | |
| SCHEMBL6356198 | 0.80 | DRD2 (0.53) | DRD2DRD1TAAR1OPRK1CALM1 | |
| Resorcinol SCHEMBL4639098 | 0.79 | OPRK1 (0.64) | DRD2DRD1TAAR1OPRK1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317068-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | OHIO UNIVERSITY | 2021-10-14 | — | — | US | disclosed |
| US-11072576-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2021-07-27 | — | — | US | disclosed |
| US-20190345094-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | OHIO UNIVERSITY | 2019-11-14 | — | — | US | disclosed |
| US-10385005-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2019-08-20 | — | — | US | disclosed |
| US-10000443-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2018-06-19 | — | — | US | disclosed |
| US-10000443-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2018-06-19 | — | — | US | disclosed |
| US-20160137585-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | OHIO UNIVERSITY (US) | 2016-05-19 | — | — | US | disclosed |
| US-9181162-B2 | Compositions and methods for glucose transport inhibition | OHIO UNIVERSITY (US) | 2015-11-10 | — | — | US | disclosed |
| US-20120121536-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | OHIO UNIVERSITY (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317068-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | SLC2A1, SLC2A4, SLC2A3 | DRD2 4380/4885DRD1 4527/4885TAAR1 4317/4885 |
| US-20160137585-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | SLC2A1, SLC2A4, SLC2A3 | DRD2 4380/4885DRD1 4527/4885TAAR1 4317/4885 |
| US-10385005-B2 | Compositions and methods for glucose transport inhibition | SLC2A1, SLC2A4, SLC2A3 | DRD2 4380/4885DRD1 4527/4885TAAR1 4317/4885 |
| US-20190345094-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | SLC2A1, SLC2A4, SLC2A3 | DRD2 4380/4885DRD1 4527/4885TAAR1 4317/4885 |
| US-11072576-B2 | Compositions and methods for glucose transport inhibition | SLC2A1, SLC2A4, SLC2A3 | DRD2 4380/4885DRD1 4527/4885TAAR1 4317/4885 |
| US-20120121536-A1 | COMPOSITIONS AND METHODS FOR GLUCOSE TRANSPORT INHIBITION | SLC2A1, SLC2A4, SLC2A3 | DRD2 4380/4885DRD1 4527/4885TAAR1 4317/4885 |
| US-10000443-B2 | Compositions and methods for glucose transport inhibition | SLC2A1, SLC2A4, SLC2A3 | DRD2 4380/4885DRD1 4527/4885TAAR1 4317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.