SCHEMBL8947211

SCHEMBL8947211

Oc1cccc(CCc2cc(O)cc(O)c2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.67
GABRG2 P18507 1/20 0.67
GABRB3 P28472 1/20 0.67
GABRA3 P34903 1/20 0.67
GABRA2 P47869 1/20 0.67
GABRB2 P47870 1/20 0.67
DRD2 P14416 2/20 0.65
DRD1 P21728 2/20 0.65
TAAR1 Q96RJ0 1/20 0.65
LTA4H P09960 1/20 0.60
CHRM2 P08172 1/20 0.59
CHRM1 P11229 1/20 0.59
CHRM3 P20309 1/20 0.59
ENPP2 Q13822 1/20 0.58
CYP3A4 P08684 2/20 0.57
CA12 O43570 1/20 0.57
ALDH1A1 P00352 1/20 0.57
CA2 P00918 1/20 0.57
LMNA P02545 1/20 0.57
CA5A P35218 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23754287 1.00 GABRA1 (0.67) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL29449650 1.00 GABRA1 (0.67) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL723832 0.93 DRD2 (0.74) GABRA1GABRG2GABRB3GABRA3GABRA2
3-Phenethylphenol SCHEMBL717571 0.86 OPRK1 (0.74) GABRA1GABRG2GABRB3GABRA3GABRA2
Lunularin SCHEMBL717118 0.84 LTA4H (0.64) DRD2DRD1TAAR1LTA4HCHRM2
SCHEMBL4949943 0.84 DRD2 (0.63) GABRA1GABRG2GABRB3GABRA3GABRA2
Resorcinol SCHEMBL4639098 0.83 OPRK1 (0.64) DRD2DRD1TAAR1CHRM2CHRM1
SCHEMBL31674607 0.83 DRD2 (0.68) GABRA1GABRG2GABRB3GABRA3GABRA2
Dihydropinosylvin SCHEMBL501070 0.83 LTA4H (0.70) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL11232474 0.83 DRD2 (0.68) DRD2DRD1TAAR1CHRM2CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114651723-B Culture medium and method for inducing one-step seedling formation of rhododendron pseudobulb plant 西南林业大学 2023-03-17 CN disclosed
CN-114651723-A Culture medium and method for inducing one-step seedling formation of rhododendron pseudobulb plant 西南林业大学 2022-06-24 CN disclosed
CN-109952286-B Skin protection composition based on dendrobe components 香港浸会大学 2022-03-22 CN disclosed
WO-2021160139-A1 9,10-DIHYDROPHENANTHRENE COMPOUNDS AND USE THEREOF IN TREATMENT OF LIVER INJURY 中国科学院上海药物研究所 2021-08-19 WO disclosed
CN-110698328-A Method for using dihydroresveratrol or stilbene derivatives and/or chemical variants thereof as antimicrobial agents 香港浸会大学 2020-01-17 CN disclosed
CN-109952286-A Skin protection composition based on Dendrobium ingredient 香港浸会大学 2019-06-28 CN disclosed
US-10188590-B2 Skin-protection composition containing Dendrobium-based ingredients HONG KONG BAPTIST UNIVERSITY (HK) 2019-01-29 US disclosed
US-10017442-B2 Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatment of tumorous pathologies HONG KONG BAPTIST UNIVERSITY (HK) 2018-07-10 US disclosed
US-10017442-B2 Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatment of tumorous pathologies HONG KONG BAPTIST UNIVERSITY (HK) 2018-07-10 US disclosed
US-10017442-B2 Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatment of tumorous pathologies HONG KONG BAPTIST UNIVERSITY (HK) 2018-07-10 US disclosed
US-20170057906-A1 SKIN-PROTECTION COMPOSITION CONTAINING DENDROBIUM-BASED INGREDIENTS HONG KONG BAPTIST UNIVERSITY 2017-03-02 US disclosed
US-20170057906-A1 SKIN-PROTECTION COMPOSITION CONTAINING DENDROBIUM-BASED INGREDIENTS HONG KONG BAPTIST UNIVERSITY 2017-03-02 US disclosed
US-20170057906-A1 SKIN-PROTECTION COMPOSITION CONTAINING DENDROBIUM-BASED INGREDIENTS HONG KONG BAPTIST UNIVERSITY 2017-03-02 US disclosed
US-20170057896-A1 Method of Using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions HONG KONG BAPTIST UNIVERSITY 2017-03-02 US disclosed
US-20170057896-A1 Method of Using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions HONG KONG BAPTIST UNIVERSITY 2017-03-02 US disclosed
US-9494864-B2 Resist overlayer film forming composition for lithography and method for manufacturing semiconductor device using the same NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-11-15 US disclosed
CN-104996421-A Application of diphenylethane compounds in dendrobium extract in plant pathogenic fungus prevention UNIV HAINAN NORMAL 2015-10-28 CN disclosed
US-20150248057-A1 RESIST OVERLAYER FILM FORMING COMPOSITION FOR LITHOGRAPHY AND METHOD FOR MANUFACTURING SEMICONDUCTOR DEVICE USING THE SAME NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-09-03 US disclosed
US-5589620-A ISOLATED FROM PLANTS; USEFUL IN TRANSFORMING VECTORS, HOST ORGANISMS AND PLANTS; PRODUCE PLANTS WHICH EXHIBIT AN INCREASED RESISTANCE TOWARDS PESTS BAYER AKTIENGESELLSCHAFT (DE) 1996-12-31 US disclosed
EP-0648839-A1 Bibenzylsynthase gene BAYER AG (DE) 1995-04-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170057906-A1 SKIN-PROTECTION COMPOSITION CONTAINING DENDROBIUM-BASED INGREDIENTS TYR, MC1R, SYMPK GABRA1 4423/4885GABRG2 4167/4885GABRB3 3190/4885
US-10017442-B2 Method of using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatment of tumorous pathologies VHL, ETV1, DHODH GABRA1 4514/4885GABRG2 4707/4885GABRB3 3692/4885
US-10188590-B2 Skin-protection composition containing Dendrobium-based ingredients TYR, MC1R, SYMPK GABRA1 4489/4885GABRG2 4381/4885GABRB3 3475/4885
US-20170057896-A1 Method of Using dihydro-resveratrol or its stilbenoid derivatives and/or chemical variants in treatments of fibrotic and diabetic conditions RNASE1, KRAS, DPP3 GABRA1 4807/4885GABRG2 4811/4885GABRB3 4268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.